Evidence map›Paper›PMID 31576761›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2019

Synthesis, cytotoxicities, and carbonic anhydrase inhibition potential of 6-(3-aryl-2-propenoyl)-2(

Sinan Bilginer, Halise Inci Gul, Feyza Sena Erdal, Hiroshi Sakagami, Serkan Levent, Ilhami Gulcin, Claudiu T Supuran

Open access · goldAbstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 25 citations in OpenAlex.

  1. Design and biological evaluation of sulfonamide-chalcone hybrids with in vitro tumor-selective cytotoxicity against oral squamous cell carcinoma: SAR, QSAR, and in silico ADME studies.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Sinan BilginerDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Ataturk University , Erzurum , Turkey.
Halise Inci GulDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Ataturk University , Erzurum , Turkey.ORCID http://orcid.org/0000-0001-6164-9602
Feyza Sena ErdalDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Ataturk University , Erzurum , Turkey.
Hiroshi SakagamiSchool of Dentistry, Meikai University Research Institute of Odontology (M-RIO), Meikai University , Sakado , Japan.
Serkan LeventDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University , Eskisehir , Turkey.
Ilhami GulcinDepartment of Chemistry, Faculty of Science, Ataturk University , Erzurum , Turkey.
Claudiu T SupuranNeurofarba Department, University Firenze , Florence , Italy.ORCID http://orcid.org/0000-0003-4262-0323
Atatürk University · TRAnadolu University · TRMeikai University · JPUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, new chalcone compounds having the chemical structure of 6-(3-aryl-2-propenoyl)-2(

Indexed as

Antineoplastic AgentsBenzoxazolesCarbonic Anhydrase InhibitorsCarbonic AnhydrasesCell Line, TumorCell SurvivalChalconeChildDrug Screening Assays, AntitumorFemaleHumansIsoenzymesMolecular StructureStructure-Activity RelationshipAntineoplastic AgentsBenzoxazolesCarbonic Anhydrase InhibitorsCarbonic AnhydrasesChalconeIsoenzymesAnticancerbenzoxazolonecarbonic anhydrasechalconecytotoxic

Identifiers

PMID31576761
PMCPMC6781194
OpenAlexW2979049134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.