Evidence map›Paper›PMID 31576614›Full record

ArticleBiotechnology and applied biochemistry2020

Macromolecular crowding effects on transcription and translation are regulated by free magnesium ion.

Xumeng Ge, Jianfeng Xu

Open access · greenAbstract read
In one paragraph

Article in Biotechnology and applied biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. AApplied and environmental microbiology · 2025
    Article
  2. Macromolecular crowding: Sensing without a sensor.Current opinion in cell biology · 2023
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Xumeng GeArkansas Biosciences Institute and College of Agriculture and Technology, Arkansas State University, Jonesboro, AR, USA.ORCID https://orcid.org/0000-0001-6272-8847
Jianfeng XuArkansas Biosciences Institute and College of Agriculture and Technology, Arkansas State University, Jonesboro, AR, USA.ORCID https://orcid.org/0000-0002-0106-2516
Arkansas State University · US

Funding

Understanding Hesitant AdoptersP20GM103429 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI Lawrence E Cornett, JERRY WARE · 2012 to 2026
$60.9M
Arkansas Biosciences InstituteArkansas IDeA Network of Biomedical Research Excellence - Research Development P20GM103429National Science Foundation 1605564NIGMS NIH HHS P20 GM103429
6 · The paper itself

Abstract

Cell-free metabolic engineering is an emerging and promising alternative platform for the production of fuels and chemicals. In recent years, macromolecular crowding effect, which is an important function in living cells but ignored in cell-free systems, has been transferred to cell-free protein synthesis (CFPS). However, inhibitory effects of crowding agents on CFPS were frequently observed, and the mechanism is unclear. In this study, free Mg

Indexed as

IonsMacromolecular SubstancesMagnesiumProteinsIonsMacromolecular SubstancesMagnesiumProteinscell-free protein synthesismagnesium ionmolecular crowdingmRNA

Identifiers

PMID31576614
PMCPMC7263881
OpenAlexW2977656820

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.