Evidence map›Paper›PMID 31576368›Full record

ArticleTransplantation direct2019

Excellent Contemporary Graft Survival for Adult Liver Retransplantation: An Australian and New Zealand Registry Analysis From 1986 to 2017.

Angus W Jeffrey, Luc Delriviere, Geoff McCaughan, Michael Crawford, Peter Angus, Robert Jones, Graeme A Macdonald, Jonathan Fawcett, Alan Wigg, John Chen and 3 more

Open access · goldAbstract read
In one paragraph

Article in Transplantation direct, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Outcomes of Adult Liver Retransplantation: A Canadian National Database Analysis.Canadian journal of gastroenterology & hepatology · 2022
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Angus W JeffreyDepartment of Gastroenterology and Hepatology, Sir Charles Gairdner Hospital, Perth, Australia.
Luc DelriviereDepartment of Gastroenterology and Hepatology, Sir Charles Gairdner Hospital, Perth, Australia.
Geoff McCaughanDepartment of Gastroenterology and Hepatology, Royal Prince Alfred Hospital, Sydney, Australia.
Michael CrawfordDepartment of Gastroenterology and Hepatology, Royal Prince Alfred Hospital, Sydney, Australia.
Peter AngusDepartment of Gastroenterology, The Austin Hospital, Melbourne, Australia.
Robert JonesDepartment of Gastroenterology, The Austin Hospital, Melbourne, Australia.
Graeme A MacdonaldDepartment of Gastroenterology and Hepatology, Princess Alexandria Hospital, Brisbane, Australia.
Jonathan FawcettDepartment of Gastroenterology and Hepatology, Princess Alexandria Hospital, Brisbane, Australia.
Alan WiggDepartment of Gastroenterology and Hepatology, Flinders Medical Centre, Adelaide, Australia.
John ChenDepartment of Gastroenterology and Hepatology, Flinders Medical Centre, Adelaide, Australia.
Ed GaneDepartment of Gastroenterology and Hepatology, Auckland City Hospital, New Zealand.
Stephen MunnDepartment of Gastroenterology and Hepatology, Auckland City Hospital, New Zealand.
Gary P JeffreyDepartment of Gastroenterology and Hepatology, Sir Charles Gairdner Hospital, Perth, Australia.
Sir Charles Gairdner Hospital · AUAustin Hospital · AUFlinders Medical Centre · AUCentenary Institute · AUUniversity of Queensland · AUUniversity of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLiver retransplantation is technically challenging, and historical outcomes are significantly worse than for first transplantations. This study aimed to assess graft and patient survival in all Australian and New Zealand liver transplantation units.

methodsA retrospective cohort analysis was performed using data from the Australia and New Zealand Liver Transplant Registry. Graft and patient survival were analyzed according to era. Cox regression was used to determine recipient, donor, or intraoperative variables associated with outcomes.

resultsBetween 1986 and 2017, Australia and New Zealand performed 4514 adult liver transplants, 302 (6.7%) of which were retransplantations (278 with 2, 22 with 3, 2 with 4). The main causes of graft failure were hepatic artery or portal vein thrombosis (29%), disease recurrence (21%), and graft nonfunction (15%). Patients retransplanted after 2000 had a graft survival of 85% at 1 year, 75% at 5 years, and 64% at 10 years. Patient survival was 89%, 81%, and 74%, respectively. This was higher than retransplantations before 2000 (

conclusionsAustralia and New Zealand have excellent survival following liver retransplantation. These contemporary results should be utilized for transplant waitlist methods.

Identifiers

PMID31576368
PMCPMC6708636
OpenAlexW2963112353

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.