Evidence map›Paper›PMID 31576217›Full record

ArticleIUCrJ2019

Ligand pathways in neuroglobin revealed by low-temperature photodissociation and docking experiments.

Chiara Ardiccioni, Alessandro Arcovito, Stefano Della Longa, Peter van der Linden, Dominique Bourgeois, Martin Weik, Linda Celeste Montemiglio, Carmelinda Savino, Giovanna Avella, Cécile Exertier and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in IUCrJ, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 2 countries.

Chiara ArdiccioniDepartment of Life and Environmental Sciences, New York-Marche Structural Biology Center (NY-MaSBiC), Polytechnic University of Marche, Ancona, Italy.ORCID https://orcid.org/0000-0003-0872-7725
Alessandro ArcovitoIstituto di Biochimica e Biochimica Clinica, Universitá Cattolica del Sacro Cuore, Largo Francesco Vito 1, 00168 Rome, Italy.ORCID https://orcid.org/0000-0002-8384-4844
Stefano Della LongaDepartment of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.ORCID https://orcid.org/0000-0002-8157-9530
Peter van der LindenEuropean Synchrotron Radiation Facility (ESRF), 38043 Grenoble, France.ORCID https://orcid.org/0000-0002-3481-0787
Dominique BourgeoisUniversité Grenoble Alpes, CEA, CNRS, IBS, 38000 Grenoble, France.ORCID https://orcid.org/0000-0002-1862-7712
Martin WeikUniversité Grenoble Alpes, CEA, CNRS, IBS, 38000 Grenoble, France.ORCID https://orcid.org/0000-0001-9297-642X
Linda Celeste MontemiglioDepartment of Biochemical Sciences 'A. Rossi Fanelli', University of Rome Sapienza, Piazzale Aldo Moro 5, 00185 Rome, Italy.ORCID https://orcid.org/0000-0002-4253-7493
Carmelinda SavinoInstitute of Molecular Biology and Pathology, National Research Council, Piazzale Aldo Moro 5, 00185 Rome, Italy.ORCID https://orcid.org/0000-0002-1602-4838
Giovanna AvellaDepartment of Biochemical Sciences 'A. Rossi Fanelli', University of Rome Sapienza, Piazzale Aldo Moro 5, 00185 Rome, Italy.
Cécile ExertierDepartment of Biochemical Sciences 'A. Rossi Fanelli', University of Rome Sapienza, Piazzale Aldo Moro 5, 00185 Rome, Italy.ORCID https://orcid.org/0000-0001-7457-6895
Philippe CarpentierEuropean Synchrotron Radiation Facility (ESRF), 38043 Grenoble, France.ORCID https://orcid.org/0000-0003-1268-7826
Thierry PrangéCiTeCoM UMR 8038 CNRS, Université Paris Descartes, Paris, France.ORCID https://orcid.org/0000-0002-7129-7396
Maurizio BrunoriDepartment of Biochemical Sciences 'A. Rossi Fanelli', University of Rome Sapienza, Piazzale Aldo Moro 5, 00185 Rome, Italy.ORCID https://orcid.org/0000-0002-7795-1635
Nathalie Colloc'hISTCT UMR 6030 CNRS Université de Caen Normandie CEA, CERVOxy Team, Centre Cyceron, Caen, France.ORCID https://orcid.org/0000-0002-2764-6026
Beatrice ValloneDepartment of Biochemical Sciences 'A. Rossi Fanelli', University of Rome Sapienza, Piazzale Aldo Moro 5, 00185 Rome, Italy.ORCID https://orcid.org/0000-0003-0058-9049
Centre National de la Recherche Scientifique · FRInstitute of Molecular Biology and Pathology · ITSapienza University of Rome · ITDélégation Paris 5 · FREuropean Synchrotron Radiation Facility · FRMarche Polytechnic University · ITUniversità Cattolica del Sacro Cuore · ITUniversity of L'Aquila · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A combined biophysical approach was applied to map gas-docking sites within murine neuroglobin (Ngb), revealing snapshots of events that might govern activity and dynamics in this unique hexacoordinate globin, which is most likely to be involved in gas-sensing in the central nervous system and for which a precise mechanism of action remains to be elucidated. The application of UV-visible microspectroscopy

Indexed as

CO photolysiscryo-trappingcrystal microspectroscopyheme proteinneuroglobinneuroprotectionoxygen bindingprotein structuresoak-and-freeze pressurizationstructural biologystructure determinationultralow-temperature X-ray crystallographyXANES

Identifiers

PMID31576217
PMCPMC6760443
OpenAlexW2957076677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.