ArticleRespirology case reports2019
Black pleural effusion: an unusual presentation of metastatic melanoma diagnosed by medical thoracoscopy.
Article in Respirology case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Etiology, pathological characteristics, and clinical management of black pleural effusion: A systematic review.Medicine · 2022Pooled it
- Primary Malignant Melanoma of the Lung.Internal medicine (Tokyo, Japan) · 2026Article
- Primary Mediastinal Malignant Melanoma Presenting With Pleural Effusion: A Case Report.Cancer reports (Hoboken, N.J.) · 2026Review
- Recurrent pleural effusion: a case of metastatic melanoma 12 years after initial diagnosis.Journal of surgical case reports · 2025Article
- Three cases of black pleural effusion.Respiratory medicine case reports · 2023Article
- The Great Mimicker: Cutaneous Metastatic Melanoma Presenting as a Non-resolving Pleural Effusion.Cureus · 2022Article
- Review
- Fade to black!Breathe (Sheffield, England) · 2020Article
- Black pleural effusion: an unusual presentation of metastatic melanoma diagnosed by medical thoracoscopy.Respirology case reports · 2019Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Melanoma presenting with black pleural effusion is rare, with only five cases reported till date. In distinction to others, this is the only case where patient did not have a prior diagnosis of melanoma and was diagnosed by thoracoscopy. Reported is the case of a 49-year-old male who presented with dyspnoea and weight loss. Patient had a large left-sided pleural effusion. Ultrasound showed thickened irregular pleura and multiloculated pleural effusion. Diagnostic pleural aspiration was performed, and fluid was black in colour and was exudative lymphocytic. Atypical cells were noted on pleural fluid cytology. Medical thoracoscopy was carried out and histopathology suggested metastatic melanoma. Patient had multiple nevi all over the body, but clinically none was indicative of melanoma. He refused skin biopsy. The case was referred to medical oncology where palliative management was planned. Patient died within two weeks of diagnosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.