Evidence map›Paper›PMID 31576189›Full record

ArticlePragmatic and observational research2019

Management Of Community-Acquired Pneumonia: An Observational Study In UK Primary Care.

Naomi Launders, Dermot Ryan, Christopher C Winchester, Derek Skinner, Priyanka Raju Konduru, David B Price

Open access · diamondAbstract read
In one paragraph

Article in Pragmatic and observational research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Naomi LaundersRespiratory Effectiveness Group, Cambridge, UK.
Dermot RyanAllergy and Respiratory Research Group, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Medical School, Edinburgh EH8 9AG, Scotland.ORCID 0000-0002-4115-7376
Christopher C WinchesterOxford PharmaGenesis, Oxford, UK.ORCID 0000-0003-3267-3990
Derek SkinnerObservational and Pragmatic Research Institute Pte Ltd, Singapore, Singapore.ORCID 0000-0002-7112-9317
Priyanka Raju KonduruObservational and Pragmatic Research Institute Pte Ltd, Singapore, Singapore.
David B PriceObservational and Pragmatic Research Institute Pte Ltd, Singapore, Singapore.ORCID 0000-0002-9728-9992
Observational & Pragmatic Research Institute · SGOxford Instruments (United Kingdom) · GBUniversity of Edinburgh · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn primary care, initial diagnosis of community-acquired pneumonia (CAP) is made on clinical judgment without radiological confirmation or knowledge of the causative organism. Use of CRB65 score has been recommended for assessing the severity of CAP and thereby determining clinical management, but it is not known how frequently these scores are used in primary care. PATIENTS AND

methodsPrimary care consultations in adults with a diagnostic code for CAP between 1 January 2009 and 31 December 2016 were extracted from the Optimum Patient Care Research Database, which at the time of data extraction had over 3.4 million patients in the UK. Episodes without antibiotic prescription on day of diagnosis were excluded, as were records describing past events. Patients admitted to hospital on day of diagnosis were excluded, but were included in exploratory analysis of CRB65 recording.

resultsIn total, 4734 episodes of CAP in adults managed in primary care between 1 January 2009 and 31 December 2016 were included. A range of investigations/observations were recorded, including pulse rate (10.7%), chest examinations (9.1%) and blood tests (5.4%). CRB65 scores were recorded in 19 (0.4%) episodes of CAP, 17 of which were after the publication of the NICE guidelines in December 2014. CRB65 recording was no more frequent in 3819 episodes referred to hospital (12, 0.3%; p=0.63), but where recorded, CRB65 scores were higher (Median: 1.0 [interquartile range: 0.5-1.0] vs 2.0 [interquartile range: 1.0-2.0], p=0.04). The most commonly prescribed antibiotic was amoxicillin (40.3%), and 85.9% of episodes had a prescription length of seven days.

conclusionCRB65 scores are seldom recorded in UK primary care. Given that these scores are embedded in UK guidelines, further work is required to assess feasibility and barriers to use of CRB65 scores in primary care.

Indexed as

antibioticsantimicrobialsCRB65guidelines adherencelower-respiratory tract infection

Identifiers

PMID31576189
PMCPMC6765344
OpenAlexW2974409367

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.