ArticleNeuropsychiatric disease and treatment2019
Subthreshold Depression Needs A Prime Time In Old Age Psychiatry? A Narrative Review Of Current Evidence.
Article in Neuropsychiatric disease and treatment, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 49 citations in OpenAlex.
- Physical frailty, depression and multimorbidity among older adults in Lima, Peru: a cross-sectional study.BMC geriatrics · 2026Article
- Cross-sectional and longitudinal functional network alterations associated with subthreshold depressive symptoms in healthy older adults.Frontiers in aging neuroscience · 2026Article
- Interleukin-6 moderates the relationship between social support, strain, and future depressive symptoms.Brain, behavior, & immunity - health · 2025Article
- Psychological Distress in Older Adults Living in Puerto Rico during COVID-19.Journal of cross-cultural gerontology · 2025Article
- Choline Alphoscerate: A Therapeutic Option for the Management of Subthreshold Depression in the Older Population.Geriatrics (Basel, Switzerland) · 2025Review
- Rising prevalence of subthreshold and major depressive symptom in South Korea: A trend analysis from 2014 and 2018.PloS one · 2025Article
- A self-help mobile messaging intervention to improve subthreshold depressive symptoms among older adults in a socioeconomically deprived region of Brazil (PRODIGITAL): a pragmatic, two-arm randomised controlled trial.Lancet regional health. Americas · 2024Article
- Age exacerbates the negative effect of depression on executive functioning in racial and ethnic minorities.Brain imaging and behavior · 2024Article
- Perceived control moderates the internalized stigma model of seeking mental health services in distressed older adults.Journal of counseling psychology · 2024Article
- The contribution of vulnerability to emotional contagion to the expression of psychological distress in older adults.PLOS mental health · 2024Article
- Age exacerbates the negative effect of depression on executive functioning in racial and ethnic minorities.Research square · 2023Article
- Late-life depression and multimorbidity trajectories: the role of symptom complexity and severity.Age and ageing · 2023Article
- Review
- The Efficacy of S-Adenosyl Methionine and Probiotic Supplementation on Depression: A Synergistic Approach.Nutrients · 2022Review
- Efficacy of psychotherapy in subthreshold depression patients: A protocol for an overview of systematic reviews and meta-analyses.Frontiers in public health · 2022Article
- Longitudinal Association between Late-Life Depression (LLD) and Frailty: Findings from a Prospective Cohort Study (MiMiCS-FRAIL).The journal of nutrition, health & aging · 2021Article
- Acupuncture for Subthreshold Depression: Study Protocol for a Randomized Controlled Trial.Frontiers in psychiatry · 2021Article
- Observational
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aims to carry out a narrative review, aiming to update the literature on subsyndromic depression (SD), which is the most prevalent depressive disorder in older adults, and no formal guidelines or consensus are dedicated to this topic. We carried out an electronic search for articles on SD. Relevant articles were retrieved from Pubmed, EMBASE and Web of Science using the search terms "subthreshold depression," "prevalence," "treatment" and "older adults" in several combinations. Original articles in English were included from inception to 1st March 2019. No clear consensus exists in the literature on its nosologic classification, diagnostic tools, causes, course, outcomes or management. SD diagnosis should base in depressive symptoms scales and DSM criteria. Treatment relies mainly on collaborative care and psychotherapy. SD is relevant in clinical practice and research in geriatric psychiatry. Given the negative outcomes and potential benefits of treatment, we recommend brief psychotherapy as first-line treatment and use of psychotropic agents in cases with greater severity and/or functional impairment in association with psychotherapy. SD can precede major depressive disorder, but it also may consist of a primary depressive disorder in older adults. Furthermore, adequate treatment of SD can prevent or reduce negative outcomes associated with depressive symptoms such as worsening of clinical comorbidities, loss of functionality, increased demand for health services, and increased mortality.
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