Evidence map›Paper›PMID 31576100›Full record

SynthesisWorld journal of gastroenterology2019

Impact of small-for-size liver grafts on medium-term and long-term graft survival in living donor liver transplantation: A meta-analysis.

Ka Wing Ma, Kelly Hiu Ching Wong, Albert Chi Yan Chan, Tan To Cheung, Wing Chiu Dai, James Yan Yue Fung, Wong Hoi She, Chung Mau Lo, Kenneth Siu Ho Chok

Open access · hybridAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in World journal of gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Complications in Post-Liver Transplant Patients.Journal of clinical medicine · 2023
    Review
  4. Review
  5. Anatomical limits in living donor liver transplantation.Korean journal of transplantation · 2022
    Review
  6. Article
  7. Observational
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Ka Wing MaDepartment of Surgery, Queen Mary Hospital, Hong Kong, China.
Kelly Hiu Ching WongLi Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Albert Chi Yan ChanDepartment of Surgery, The University of Hong Kong, Hong Kong, China.
Tan To CheungDepartment of Surgery, The University of Hong Kong, Hong Kong, China.
Wing Chiu DaiDepartment of Surgery, Queen Mary Hospital, Hong Kong, China.
James Yan Yue FungDepartment of Medicine, Queen Mary Hospital, Hong Kong, China.
Wong Hoi SheDepartment of Surgery, Queen Mary Hospital, Hong Kong, China.
Chung Mau LoDepartment of Surgery, The University of Hong Kong, Hong Kong, China.
Kenneth Siu Ho ChokDepartment of Surgery, The University of Hong Kong, Hong Kong, China. chok6275@hku.hk.
Queen Mary Hospital · CNUniversity of Hong Kong · HKChinese University of Hong Kong · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSmall-for-size grafts (SFSGs) in living donor liver transplantation (LDLT) could optimize donor postoperative outcomes and also expand the potential donor pool. Evidence on whether SFSGs would affect medium-term and long-term recipient graft survival is lacking.

aimTo evaluate the impact of small-for-size liver grafts on medium-term and long-term graft survival in adult to adult LDLT.

methodsA systematic review and meta-analysis were performed by searching eligible studies published before January 24, 2019 on PubMed, EMBASE, and Web of Science databases. The primary outcomes were 3-year and 5-year graft survival. Incidence of small-for-size syndrome and short term mortality were also extracted.

resultsThis meta-analysis is reported according to the guidelines of the PRISMA 2009 Statement. Seven retrospective observational studies with a total of 1821 LDLT recipients were included in the meta-analysis. SFSG is associated with significantly poorer medium-term graft survival. The pooled odds ratio for 3-year graft survival was 1.58 [95% confidence interval 1.10-2.29,

conclusionSFSG is associated with inferior medium-term but not long-term graft survival. Comparable long-term graft survival based on liver graft size shows that smaller grafts could be accepted for LDLT with appropriate flow modulatory measures. Close follow-up for graft function is warranted within 3 years after liver transplantation.

Indexed as

Graft SurvivalLiving DonorsAdultAge FactorsAllograftsChildDonor SelectionHumansLiverLiver TransplantationOrgan SizePractice Guidelines as TopicRisk FactorsTime FactorsTreatment OutcomeGraft survivalLiving donor liver transplantationSmall-for-size graftsSmall-for-size syndrome

Identifiers

PMID31576100
PMCPMC6767984
OpenAlexW2977004726

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.