Evidence map›Paper›PMID 31576089›Full record

GuidelineWorld journal of gastroenterology2019

Chinese guidelines on management of hepatic encephalopathy in cirrhosis.

Xiao-Yuan Xu, Hui-Guo Ding, Wen-Gang Li, Ji-Dong Jia, Lai Wei, Zhong-Ping Duan, Yu-Lan Liu, En-Qiang Ling-Hu, Hui Zhuang, Chinese Society Of Hepatology and 1 more

Registry-linked trialAbstract readPractice Guideline
In one paragraph

Guideline in World journal of gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05140837 (Early Diagnosis and Timely Treatment of Cirrhotic Patients With Minimal Hepatic Encephalopathy), which is not on this map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05140837 unknown statusnot on this mapstarted 2021, after this paper: background citation

Early Diagnosis and Timely Treatment of Cirrhotic Patients With Minimal Hepatic Encephalopathy (CHESS-NCRCID 2106)

TypeobservationalSponsorHepatopancreatobiliary Surgery Institute of Gansu ProvinceRan2021 to 2024Enrolled10,000ConditionsHepatic Encephalopathy, CirrhosisArmsPsychometric hepatic encephalopathy score & Stroop test, Drug therapy
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  9. [Protective effect of knock-down the expression ofBeijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025
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  11. Review
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  18. Low Prealbumin Levels Were Associated with Increased Frequency of Hepatic Encephalopathy in Hepatitis B Virus (HBV)-Related Decompensated Cirrhosis.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiao-Yuan XuDepartment of Infectious Diseases, Peking University First Hospital, Beijing 100034, China. xiaoyuanxu6@163.com.
Hui-Guo DingHepatology and Digestion Center, Beijing You-An Hospital, Capital Medical University, Beijing 100069, China.
Wen-Gang LiDepartment of Liver Oncology, Cancer Radiation Therapy Center, Fifth Medical Center, PLA General Hospital, Beijing 100039, China.
Ji-Dong JiaHepatology Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
Lai WeiHepatobiliary and Pancreatic Department, Beijing Tsinghua Changgeng Hospital, Beijing 102218, China.
Zhong-Ping DuanArtificial Liver Center, Beijing You-An Hospital, Capital Medical University, Beijing 100069, China.
Yu-Lan LiuDepartment of Gastroenterology, Peking University People's Hospital, Beijing 100044, China.
En-Qiang Ling-HuDepartment of Gastroenterology, First Medical Center, PLA General Hospital, Beijing 100853, China.
Hui ZhuangDepartment of Pathogenic Biology, Peking University Health Science Center, Beijing 100191, China.
Chinese Society Of Hepatology
Chinese Medical Association

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Chinese Society of Hepatology developed the current guidelines on the management of hepatic encephalopathy in cirrhosis based on the published evidence and the panelists' consensus. The guidelines provided recommendations for the diagnosis and management of hepatic encephalopathy (HE) including minimal hepatic encephalopathy (MHE) and overt hepatic encephalopathy, emphasizing the importance on screening MHE in patients with end-stage liver diseases. The guidelines emphasized that early identification and timely treatment are the key to improve the prognosis of HE. The principles of treatment include prompt removal of the cause, recovery of acute neuropsychiatric abnormalities to baseline status, primary prevention, and secondary prevention as soon as possible.

Indexed as

ChinaConsensusEnd Stage Liver DiseaseGastroenterologyHepatic EncephalopathyHumansLiver CirrhosisPrognosisSecondary PreventionSocieties, MedicalTime FactorsDiagnosisHepatic encephalopathyLiver cirrhosisTherapy

Identifiers

PMID31576089
PMCPMC6767982

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.