Observational studyScientific reports2019
Worldwide Age at Onset of Female Breast Cancer: A 25-Year Population-Based Cancer Registry Study.
Observational study in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.
- Triple-negative breast cancer prevalence in Africa: a systematic review and meta-analysis.BMJ open · 2022Pooled it
- Aging-associated differences in mammary tumor-initiating populations and immune evasion pathways in breast cancer.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Impact of Ethnic Differences and HER2 Protein Expression on the Age at Breast Cancer Diagnosis: A Mixed Methods Study.Cancer management and research · 2026Article
- Retrospective Cohort Analysis of Outcomes Among Young Onset Breast Cancer Patients in Kijabe, Kenya.The Journal of surgical research · 2025Article
- A case of long-term relief from bleeding due to fungating breast cancer in an elderly patient after 8-Gy single-fraction radiation therapy.International cancer conference journal · 2025Article
- Global patterns and trends in cancer-related premature death and their impact on life expectancy across 185 countries: a population-based analysis.Military Medical Research · 2025Article
- Serum Hepcidin Levels in Breast Cancer Patients: Investigating the Correlation to Tumor Stage-A Cross-Sectional Study.Health science reports · 2025Article
- Prevalence and clinicopathological features of human epidermal growth factor receptor-2-low breast cancers: A single-center experience.The Journal of international medical research · 2025Observational
- Survival Rate of Breast Cancer and Related Factors in Iran: A 27-Year Follow-Up.Iranian journal of public health · 2025Article
- Universal vs. ASCO guidelines-based germline genetic testing for newly diagnosed breast cancer patients in resource-restricted settings.Oncology reviews · 2025Article
- BRCA1/2 mutations and outcomes among Middle Eastern patients with early-onset breast cancer in Oman.The oncologist · 2024Article
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- Article
- Genetic Testing Among Breast Cancer Patients in the Eastern Region of Saudi Arabia: Single-Center Experience.Journal of epidemiology and global health · 2024Article
- Development of a model to predict the age at breast cancer diagnosis in a global population.Scientific reports · 2024Article
- Out-of-pocket payment and financial risk protection for breast cancer treatment: a prospective study from India.The Lancet regional health. Southeast Asia · 2024Article
- Article
- Breast cancer in women by HIV status: A report from the South African National Cancer Registry.PloS one · 2024Article
- Using Telemedicine to Care for Patients with Breast Cancer: A Natural Quasi-Experimental Study.Journal of cancer & allied specialties · 2024Article
- Bibliometric analysis of global research trends between gut microbiota and breast cancer: from 2013 to 2023.Frontiers in microbiology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A higher frequency of early onset female breast cancers (BC) has been observed in low/middle income countries than in high income countries. We quantified the role of population ageing to this pattern using data from all population-based cancer registries (CRs) worldwide. Patients' median age at BC onset and that of the general population were extracted for CRs listed in volumes VI (1983-1987 years) through XI (2008-2012 years) of Cancer Incidence in Five Continents. Their association was assessed at cross-sectional level by linear regression model and longitudinally considering 25-year ageing of the population in long-standing CRs listed at the beginning and at the end of the study. During 2008-2012, each one-year increase of population ageing was associated with a nearly ½ year increase of age at BC diagnosis. Population demographics explained forty-two percent of the age variance for BC. In 1983-1987, long-standing CRs with a median age at BC below age 61.8 years showed an increase of age at BC after 25-years. Worldwide, age at BC diagnosis essentially reflected the median age of the population. Changes in BC detection methodology likely lessened this association. Nevertheless, the elevated absolute number of BCs in young populations deserves strategies of BC prevention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.