Evidence map›Paper›PMID 31575776›Full record

ArticlemBio2019

Unraveling Melanin Biosynthesis and Signaling Networks in Cryptococcus neoformans.

Dongpil Lee, Eun-Ha Jang, Minjae Lee, Sun-Woo Kim, Yeonseon Lee, Kyung-Tae Lee, Yong-Sun Bahn

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 101 citations in OpenAlex.

  1. Set202 is a histone lysine methyltransferase that enablesbioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. mBio · 2025
    Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Regulation of melanin production in fungi.Frontiers in fungal biology · 2025
    Review
  13. Review
  14. Is Cryptococcus neoformans a pleomorphic fungus?Current opinion in microbiology · 2024
    Review
  15. Article
  16. Article
  17. Mechanisms and Virulence Factors ofJournal of fungi (Basel, Switzerland) · 2024
    Review
  18. Two ZnApplied and environmental microbiology · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Dongpil LeeDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
Eun-Ha JangDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
Minjae LeeDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
Sun-Woo KimDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
Yeonseon LeeDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
Kyung-Tae LeeDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
Yong-Sun BahnDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea ysbahn@yonsei.ac.kr.
Yonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melanin is an antioxidant polyphenol pigment required for the pathogenicity of many fungal pathogens, but comprehensive regulatory mechanisms remain unidentified. In this study, we systematically analyzed melanin-regulating signaling pathways in

Indexed as

Cryptococcus neoformansGene Expression ProfilingGene Expression Regulation, FungalLaccaseMelaninsProtein KinasesSignal TransductionTranscription FactorsLaccaseMelaninsProtein KinasesTranscription FactorsBzp4Gsk3Hob1Mbs1RAM pathwayTOR pathwayUsv101

Identifiers

PMID31575776
PMCPMC6775464
OpenAlexW2978897292

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.