Evidence map›Paper›PMID 31575775›Full record

ArticlemBio2019

Establishment of Chronic Typhoid Infection in a Mouse Carriage Model Involves a Type 2 Immune Shift and T and B Cell Recruitment to the Gallbladder.

Juan F González, Jonathan Kurtz, David L Bauer, Regan Hitt, James Fitch, Amy Wetzel, Krista La Perle, Peter White, James McLachlan, John S Gunn

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. CD4Nature communications · 2026
    Article
  2. EnhancedInfection and immunity · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. The footprint of gut microbiota in gallbladder cancer: a mechanistic review.Frontiers in cellular and infection microbiology · 2024
    Review
  7. Review
  8. The Abundance and Organization ofInfection and immunity · 2021
    Article
  9. Revisiting PersistentPathogens (Basel, Switzerland) · 2021
    Review
  10. Frontiers in cellular and infection microbiology · 2021
    Article
  11. Control of PersistentPathogens (Basel, Switzerland) · 2020
    Article
  12. Infection and immunity · 2020
    Article
  13. Microorganisms · 2020
    Article
  14. Review
  15. Frontiers in cellular and infection microbiology · 2020
    Review
  16. Immune exhaustion in bacterial infections: mechanisms, consequences, and therapeutic implications.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Juan F GonzálezCenter for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Jonathan KurtzDepartment of Microbiology & Immunology, Tulane University Health Sciences Center, New Orleans, Louisiana, USA.
David L BauerDepartment of Microbiology & Immunology, Tulane University Health Sciences Center, New Orleans, Louisiana, USA.
Regan HittCenter for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
James FitchThe Institute for Genomic Medicine, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Amy WetzelThe Institute for Genomic Medicine, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Krista La PerleDepartment of Veterinary Biosciences, Comparative Pathology and Mouse Phenotyping Shared Resource, The Ohio State University, Columbus, Ohio, USA.
Peter WhiteDepartment of Pediatrics, College of Medicine, The Ohio State University, Columbus, Ohio, USA.
James McLachlanDepartment of Microbiology & Immunology, Tulane University Health Sciences Center, New Orleans, Louisiana, USA.
John S GunnCenter for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA John.Gunn@nationwidechildrens.org.
The Ohio State University · USNationwide Children's Hospital · USTulane University · US

Funding

Using combination adjuvants to direct and control immune responses at the intestinal mucosaU01AI124289 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI MCLACHLAN, JAMES B · 2016 to 2020
$2.4M
Organ-specific CD4 T cell responses regulate Salmonella persistenceR01AI103343 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI MCLACHLAN, JAMES B · 2013 to 2016
$1.5M
NIAID NIH HHS R01 AI103343NIAID NIH HHS U01 AI124289
6 · The paper itself

Abstract

Typhoid fever, caused primarily by

Indexed as

AnimalsBiofilmsB-LymphocytesCholecystitisChronic DiseaseDietDisease Models, AnimalGallbladderLymphocyte CountMaleMiceRNA-SeqSalmonella typhiTh1 CellsTh2 CellsTranscriptomebiofilmchronic carriageSalmonella

Identifiers

PMID31575775
PMCPMC6775463
OpenAlexW2978090650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.