ArticlemBio2019
Arachidonic Acid Kills Staphylococcus aureus through a Lipid Peroxidation Mechanism.
Open access · goldAbstract read
In one paragraph
Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
55 citing papers in PubMed, 91 citations in OpenAlex.
- Article
- Metabolic reprogramming promotesMicrobiology (Reading, England) · 2026Article
- Susceptibility of the Oral Commensal BacteriumInternational journal of molecular sciences · 2026Article
- Induction effect of exogenous arachidonic acid on resistance to white leaf spot in maize.BMC plant biology · 2026Article
- Non-canonical stringent response signaling mediates antimicrobial fatty acid sensitivity inbioRxiv : the preprint server for biology · 2026Article
- Extracellular wax ester biosynthesis by staphylococcal lipases detoxifies skin fatty acids and shapes interspecies competition.The ISME journal · 2026Article
- Activation of the Spx redox sensor counters cysteine-driven Fe(II) depletion under disulfide stress.bioRxiv : the preprint server for biology · 2025Article
- Linoleic Hydroperoxides Are Potent Hyperoxidative Agents of Sensitive and Robust Typical 2-Cys Peroxiredoxins.Antioxidants (Basel, Switzerland) · 2025Article
- Changes in ferroptosis-related molecular expression in macrophages of community-acquired pneumonia patients and their associated with the disease progression.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025Article
- Defects in anaplerotic metabolism sensitizeMicrobiology spectrum · 2025Article
- Live fast, die young: neutrophils streamline their metabolism to maximize inflammation.Infection and immunity · 2025Review
- Effect of Tunicamycin on Viability, Motility, Reactive Oxygen Species, Nitric Oxide, and Lipid Peroxidation in Boar Sperm.Animals : an open access journal from MDPI · 2025Article
- Anti-staphylococcal fatty acids: mode of action, bacterial resistance and implications for therapeutic application.Microbiology (Reading, England) · 2025Review
- Gram-positive pathogens, inflammation, and the host lipid environment.Current opinion in microbiology · 2025Review
- Cannabidiol (CBD) Acts as an Antioxidant onAntibiotics (Basel, Switzerland) · 2025Article
- Beyond nutritional immunity: immune-stressing challenges basic paradigms of immunometabolism and immunology.Frontiers in nutrition · 2025Review
- Regulating arachidonic acid metabolism: a novel strategy to prevent colorectal inflammatory cancer transformation.Journal of Cancer · 2025Review
- Docosahexaenoic Acid-Driven Metabolic Reprogramming as an Attractive Anti-Infection Strategy to Potentiate β-Lactam Antibiotic Efficacy.Research (Washington, D.C.) · 2025Article
- Bacterial acquisition of host fatty acids has far-reaching implications on virulence.Microbiology and molecular biology reviews : MMBR · 2024Review
- Emerging mechanisms of lipid peroxidation in regulated cell death and its physiological implications.Cell death & disease · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
William N BeaversDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Andrew J MonteithDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Venkataraman AmarnathDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Raymond L MernaughDepartment of Biochemistry, Vanderbilt University, Nashville, Tennessee, USA.
L Jackson RobertsDepartment of Pharmacology, Vanderbilt University, Nashville, Tennessee, USA.
Walter J ChazinDepartment of Biochemistry, Vanderbilt University, Nashville, Tennessee, USA.
Sean S DaviesDepartment of Pharmacology, Vanderbilt University, Nashville, Tennessee, USA.ORCID 0000-0001-9879-8062
Eric P SkaarDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA eric.skaar@vumc.org.
Vanderbilt University · USVanderbilt University Medical Center · US
Funding
Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8MVANDERBILT UNIVERSITY CTSA FOR PEDIATRIC RESEARCHUL1RR024975 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$45.7MTranslational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9MShop Module CoreP30EY008126 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI David J. Calkins · 1989 to 2026
$19.6MVANTAGE:Consolidation to create the Vanderbilt Technologies for Advanced GenomicsG20RR030956 · NCRR · VANDERBILT UNIVERSITY · PI PIETENPOL, JENNIFER A · 2010 to 2010
$8.7MVanderbilt Infection Pathogenesis and Epidemiology Research Training ProgramT32AI007474 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KALAMS, SPYROS A · 1995 to 2025
$6.9MImmunobiology of Blood and Vascular Systems Training ProgramT32HL069765 · NHLBI · VANDERBILT UNIVERSITY · PI HAWIGER, JACK J · 2002 to 2016
$6.5MPathobiology of heme inducible transporters in Gram positive pathogensR01AI073843 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SKAAR, ERIC P · 2009 to 2025
$5.9MMechanism and function of heme-iron utilization in staphylococcal pathogenesisR01AI069233 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SKAAR, ERIC P · 2006 to 2020
$5.6MThe impact of dietary manganese on the immune response during Staphylococcus aureus infection of the heartF32HL144081 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MONTEITH, ANDREW J · 2018 to 2020
$143kNCI NIH HHS P30 CA068485NCRR NIH HHS G20 RR030956NCRR NIH HHS UL1 RR024975NEI NIH HHS P30 EY008126NHLBI NIH HHS F32 HL144081NHLBI NIH HHS T32 HL069765NIAID NIH HHS R01 AI069233NIAID NIH HHS R01 AI073843NIAID NIH HHS T32 AI007474NIDDK NIH HHS P30 DK058404
Abstract
PubMed holds no abstract for this paper.
Indexed as
AnimalsAnti-Bacterial AgentsArachidonic AcidBrainDose-Response Relationship, DrugDrug Resistance, BacterialFemaleKidneyLipid PeroxidationLipidsMiceMice, Inbred BALB CMicrobial Sensitivity TestsMutationNeutrophilsOxidative StressAnti-Bacterial AgentsArachidonic AcidisolevuglandinLipidsReactive Oxygen SpeciesTeichoic Acidsarachidonic acidisolevuglandinsMRSApathogenesispolyunsaturated fatty acidsStaphylococcus aureuswall teichoic acids
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What OpenQuestion holds
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.