Evidence map›Paper›PMID 31575648›Full record

ArticleDevelopment (Cambridge, England)2019

Muscle-selective RUNX3 dependence of sensorimotor circuit development.

Yiqiao Wang, Haohao Wu, Pavel Zelenin, Paula Fontanet, Simone Wanderoy, Charles Petitpré, Glenda Comai, Carmelo Bellardita, Yongtao Xue-Franzén, Rosa-Eva Huettl and 7 more

Open access · hybridAbstract read
In one paragraph

Article in Development (Cambridge, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Influencers in the Somatosensory System: Extrinsic Control of Sensory Neuron Phenotypes.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 4 countries.

Yiqiao WangDepartment of Neuroscience, Karolinska Institutet, Stockholm 17177, Sweden.
Haohao WuDepartment of Neuroscience, Karolinska Institutet, Stockholm 17177, Sweden.
Pavel ZeleninDepartment of Neuroscience, Karolinska Institutet, Stockholm 17177, Sweden.
Paula FontanetDepartment of Neuroscience, Karolinska Institutet, Stockholm 17177, Sweden.
Simone WanderoyDepartment of Neuroscience, Karolinska Institutet, Stockholm 17177, Sweden.
Charles PetitpréDepartment of Neuroscience, Karolinska Institutet, Stockholm 17177, Sweden.
Glenda ComaiDepartment of Developmental and Stem Cell Biology, Institut Pasteur, CNRS UMR3738, Paris 75015, France.
Carmelo BellarditaDepartment of Neuroscience, University of Copenhagen, Copenhagen 2200, Denmark.
Yongtao Xue-FranzénDepartment of Neuroscience, Karolinska Institutet, Stockholm 17177, Sweden.
Rosa-Eva HuettlHelmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics, Neuherberg 85764, Germany.
Andrea B HuberHelmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics, Neuherberg 85764, Germany.
Shahragim TajbakhshDepartment of Developmental and Stem Cell Biology, Institut Pasteur, CNRS UMR3738, Paris 75015, France.
Ole KiehnDepartment of Neuroscience, Karolinska Institutet, Stockholm 17177, Sweden.
Patrik ErnforsUnit of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm 17177, Sweden.
Tatiana G DeliaginaDepartment of Neuroscience, Karolinska Institutet, Stockholm 17177, Sweden.
François LallemendDepartment of Neuroscience, Karolinska Institutet, Stockholm 17177, Sweden francois.lallemend@ki.se saida.hadjab@ki.se.ORCID 0000-0001-5484-0011
Saida HadjabDepartment of Neuroscience, Karolinska Institutet, Stockholm 17177, Sweden francois.lallemend@ki.se saida.hadjab@ki.se.ORCID 0000-0001-7953-8396
Karolinska Institutet · SECentre National de la Recherche Scientifique · FRHelmholtz Zentrum München · DEUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The control of all our motor outputs requires constant monitoring by proprioceptive sensory neurons (PSNs) that convey continuous muscle sensory inputs to the spinal motor network. Yet the molecular programs that control the establishment of this sensorimotor circuit remain largely unknown. The transcription factor RUNX3 is essential for the early steps of PSNs differentiation, making it difficult to study its role during later aspects of PSNs specification. Here, we conditionally inactivate

Indexed as

AnimalsCell DifferentiationCells, CulturedCore Binding Factor Alpha 3 SubunitFemaleGanglia, SpinalGene Expression Regulation, DevelopmentalHomeodomain ProteinsLIM-Homeodomain ProteinsMaleMiceMice, Inbred C57BLMicrofilament ProteinsMotor NeuronsMuscle ProteinsNerve Growth FactorsAvil protein, mouseCore Binding Factor Alpha 3 SubunitHb9 protein, mouseHomeodomain ProteinsIsl2 protein, mouseLbx1h protein, mouseLIM-Homeodomain ProteinsMicrofilament ProteinsMuscle ProteinsNerve Growth FactorsTranscription FactorsDorsal root gangliaNeuronal specificationNeurotrophinsSensorimotor circuitSensory system

Identifiers

PMID31575648
PMCPMC6826036
OpenAlexW2978756583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.