ArticlePediatrics2019
Associations Between Opioid Prescribing Patterns and Overdose Among Privately Insured Adolescents.
Article in Pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Predictors of fatal and nonfatal overdose after prescription of opioids for chronic pain: a systematic review and meta-analysis of observational studies.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023Pooled it
- Mental disorder and opioid overdose: a systematic review.Social psychiatry and psychiatric epidemiology · 2022Pooled it
- Opioid use and misuse in children, adolescents, and young adults with cancer: a systematic review of the literature.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Pooled it
- Virtual Reality for the Management of Postoperative Pain and Anxiety in Children and Adolescents Undergoing Nuss Repair of Pectus Excavatum: Randomized Controlled Trial.JMIR perioperative medicine · 2026Trial
- Prescription Opioid Misuse Among High School Athletes During the Opioid Prescribing Limit Law Era: YRBSS 2017-2023.Healthcare (Basel, Switzerland) · 2026Article
- Proportional Trends in Pediatric Opioid Prescribing Between 2005 and 2016 by Age Group, Sex, Ethnicity, Race, Language, and Payer Status from a Large Children's Hospital in the Southwest United States.Children (Basel, Switzerland) · 2024Article
- Posterior spinal fusion for adolescent idiopathic scoliosis and the impact of postoperative intravenous dexamethasone supplementation.Paediatric & neonatal pain · 2024Article
- Article
- Anxiety and Mood Disorders Impacting Physician Opioid Prescribing in the Pediatric Hospital Setting.Journal of clinical psychology in medical settings · 2021Article
- Opioid Prescribing to US Children and Young Adults in 2019.Pediatrics · 2021Article
- Assessing opioid overdose risk: a review of clinical prediction models utilizing patient-level data.Translational research : the journal of laboratory and clinical medicine · 2021Review
- Adverse Events And Emergency Department Opioid Prescriptions In Adolescents.Health affairs (Project Hope) · 2021Article
- Assessment of Prescription Opioid Medical Use and Misuse Among Parents and Their Adolescent Offspring in the US.JAMA network open · 2021Article
- Diagnosis and Treatment of Chronic Neuropathic and Mixed Pain in Children and Adolescents: Results of a Survey Study amongst Practitioners.Children (Basel, Switzerland) · 2020Article
- Age disparities in six-month treatment retention for opioid use disorder.Drug and alcohol dependence · 2020Article
- Association of Opioid Prescribing Patterns With Prescription Opioid Overdose in Adolescents and Young Adults.JAMA pediatrics · 2020Article
- Psychometric validation of the AOSL scale using confirmatory factor analysis: A nationally representative sample.Journal of the American Pharmacists Association : JAPhAArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesLittle is known about the risk for overdose after opioid prescription. We assessed associations between the type of opioid, quantity dispensed, daily dose, and risk for overdose among adolescents who were previously opioid naive.
methodsRetrospective analysis of 1 146 412 privately insured adolescents ages 11 to 17 years in the United States captured in the Truven MarketScan commercial claims data set from January 2007 to September 2015. Opioid overdose was defined as any emergency department visit, inpatient hospitalization, or outpatient health care visit during which opioid overdose was diagnosed.
resultsAmong our cohort, 725 participants (0.06%) experienced an opioid overdose, and the overall rate of overdose events was 28 events per 100 000 observed patient-years. Receiving ≥30 opioid tablets was associated with a 35% increased risk for overdose compared to receiving ≤18 tablets (hazard ratio [HR] = 1.35; 95% confidence interval: 1.05-1.73;
conclusionsOne of 1600 (0.06%) previously opioid-naive adolescents who received a prescription for opioids experienced an opioid overdose a median of 1.75 years later that resulted in medical care. Preexisting mental health conditions, use of tramadol, and higher number of dispensed tablets (>30 vs <18) were associated with an increased risk of opioid overdose.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.