Evidence map›Paper›PMID 31575579›Full record

ArticleBMJ open2019

Time from diagnosis to treatment of colorectal cancer in a South Australian clinical registry cohort: how it varies and relates to survival.

David Roder, Christos Stelios Karapetis, Ian Olver, Dorothy Keefe, Robert Padbury, James Moore, Rohit Joshi, David Wattchow, Dan L Worthley, Caroline Louise Miller and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

David RoderCancer Research Institute, University of South Australia, Adelaide, South Australia, Australia David.Roder@unisa.edu.au.ORCID 0000-0001-6442-4409
Christos Stelios KarapetisMedical Oncology, Flinders University, Adelaide, South Australia, Australia.
Ian OlverCancer Research Institute, University of South Australia, Adelaide, South Australia, Australia.
Dorothy KeefeSouth Australian Cancer Service, South Australia Department of Health, Adelaide, South Australia, Australia.
Robert PadburyMedical Oncology, Flinders University, Adelaide, South Australia, Australia.
James MooreAdelaide Medical School, The University of Adelaide, Adelaide, South Australia, Australia.
Rohit JoshiAdelaide Medical School, The University of Adelaide, Adelaide, South Australia, Australia.
David WattchowMedical Oncology, Flinders University, Adelaide, South Australia, Australia.
Dan L WorthleyGastrointestinal Cancer Biology, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
Caroline Louise MillerPopulation Health, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.ORCID 0000-0001-9723-8047
Carol HoldenPopulation Health, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.ORCID 0000-0002-4011-6628
Elizabeth BuckleyCancer Research Institute, University of South Australia, Adelaide, South Australia, Australia.
Kate PowellPopulation Health, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
Dianne Buranyi-TrevartonSouth Australian Cancer Service, South Australia Department of Health, Adelaide, South Australia, Australia.
Kellie FuscoCancer Research Institute, University of South Australia, Adelaide, South Australia, Australia.
Timothy PriceAdelaide Medical School, The University of Adelaide, Adelaide, South Australia, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesSome early studies indicated lower survival with longer time from diagnosis to cancer treatment, but others showed the reverse. We investigated time to treatment of colorectal cancer and associations with survival. SETTING AND

participantsClinical registry data for colorectal cancer cases diagnosed in 2000-2010 at four major public hospitals in South Australia and treated by surgery (n=1675), radiotherapy (n=616) and/or systemic therapy (n=1556).

designA historic cohort design, with rank-order tests for ordinal clinical and sociodemographic predictors and multiple logistic regression for comparing time from diagnosis to treatment. Unadjusted Kaplan-Meier estimates and adjusted Cox proportional hazards regression were used to investigate disease-specific survival by time to treatment. OUTCOME MEASURES: Time to treatment and survival from diagnosis to death from colorectal cancer.

resultsTreatment (any type) commenced for 87% of surgical cases

conclusionsThe lower survival

Indexed as

AgedAged, 80 and overAge FactorsColorectal NeoplasmsFemaleHumansKaplan-Meier EstimateMaleMiddle AgedProportional Hazards ModelsRegistriesSouth AustraliaSurvival AnalysisTime FactorsTime-to-Treatmentcolorectal surgeryOncology epidemiologyprotocols & guidelinespublic healthquality in healthcare

Identifiers

PMID31575579
PMCPMC6797269

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.