Evidence map›Paper›PMID 31575575›Full record

ArticleBMJ open2019

Disease burden and cost of hidradenitis suppurativa: a retrospective examination of US administrative claims data.

Jessica Marvel, Anna Vlahiotis, Amy Sainski-Nguyen, Tina Willson, Alexandra Kimball

Abstract read
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
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  4. Review
  5. Patient journey and disparities in the diagnosis and treatment of patients with hidradenitis suppurativa.JID innovations : skin science from molecules to population health · 2026
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  8. Diagnostic wandering in hidradenitis suppurativa: A nationwide cohort study.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jessica MarvelDepartment of Health Economics and Outcomes Research, Novartis Pharmaceuticals Corp, East Hanover, New Jersey, USA jessica.marvel@novartis.com.ORCID 0000-0002-0757-5865
Anna VlahiotisDepartment of Life Sciences, IBM Watson Health, Bethesda, Maryland, USA.
Amy Sainski-NguyenDepartment of Life Sciences, IBM Watson Health, Bethesda, Maryland, USA.
Tina WillsonDepartment of Life Sciences, IBM Watson Health, Bethesda, Maryland, USA.
Alexandra KimballDepartment of Dermatology, Harvard Medical School, Boston, Massachusetts, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesHidradenitis suppurativa (HS) causes substantial morbidity and quality-of-life impairment. We examined demographic/clinical characteristics of patients with HS and treatment patterns, prevalence and healthcare resource utilisation/expenditures related to HS in the real-world.

designRetrospective claims data of MarketScan Commercial, Medicare Supplemental and Medicaid databases (2009-2014).

settingUSA.

participantsPatients aged ≥12 years with ≥3 non-diagnostic outpatient or inpatient claims with an HS diagnosis code and ≥12 months continuous enrolment with medical and pharmacy benefits before (preindex) and after (postindex) the earliest diagnosis of HS (index) were included.

resultsThere were 11 325 Commercial/Medicare patients (mean age 37.4 years) and 5164 Medicaid patients (mean age 28.3 years). HS was more common in Medicaid than Commercial/Medicare patients (0.301% and 0.098%, respectively, in 2014). Cellulitis and psychiatric disorders were the most common comorbidities and oral antibiotics and narcotics were the most frequently prescribed drugs preindex, with ≥10% increase postindex in both populations. HS-related inpatient costs decreased while outpatient costs increased from preindex to postindex. Medicaid patients had several risk factors that may be associated with poor outcomes (eg, high rates of prescription pain medication use, comorbidities, drug discontinuation/interruption/holiday, emergency department (ED) visits and hospitalisation).

conclusionsCommercial/Medicare and Medicaid HS beneficiaries experience high comorbidity burden but use different treatment modalities to manage HS. Results suggest a substantial unmet need exists among this patient population, with Medicaid patients experiencing a particularly high burden of disease and expensive healthcare resource utilisation.

Indexed as

Cost of IllnessAdultFemaleHealth Care CostsHidradenitis SuppurativaHumansMaleMedicaidMedicarePrevalenceRetrospective StudiesUnited Statescomorbidityhidradenitis suppurativaprevalenceresource utilizationtreatmentstumor necrosis factor inhibitors

Identifiers

PMID31575575
PMCPMC6797383

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.