Evidence map›Paper›PMID 31575554›Full record

ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2019

Disparities in Cancer Incidence and Trends among American Indians and Alaska Natives in the United States, 2010-2015.

Stephanie C Melkonian, Melissa A Jim, Donald Haverkamp, Charles L Wiggins, Jeffrey McCollum, Mary C White, Judith S Kaur, David K Espey

Registry-linked trialAbstract read
In one paragraph

Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06207864 (Participant Engagement - Cancer Genome Sequencing), which is not on this map. Cited by 66 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06207864 narecruitingnot on this mapstarted 2022, after this paper: background citation

Participant Engagement - Cancer Genome Sequencing (PE-CGS) Research Center: Engagement of American Indians of Southwestern Tribal Nations in Cancer Genome Sequencing

TypeinterventionalSponsorNew Mexico Cancer Research AllianceRan2022 to 2030Enrolled1,001ConditionsMalignant NeoplasmArmsBiospecimen Collection, Return of Results, Survey Administration
3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 2 syntheses or guidelines pooled it, 84 citations in OpenAlex.

  1. Pooled it
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  5. Racial and Ethnic Differences in Gastric Cancer by Stage of Diagnosis in the United States (2009-2019).Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
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  7. Colorectal Cancer in the American Indian and Alaska Native Community: A Holistic Review.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026
    Review
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  11. Comorbidities among American Indian and Alaska Native People with Cancer: A Surveillance, Epidemiology, and End Results-Medicare Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
  12. Modeling Reporting Delay in Cancer Incidence Counts in the Evolving US and Canadian Population-Based Cancer Registry Environment.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Stephanie C MelkonianDivision of Cancer Prevention and Control, Centers for Disease Control and Prevention, Albuquerque, New Mexico. mzv3@cdc.gov.
Melissa A JimDivision of Cancer Prevention and Control, Centers for Disease Control and Prevention, Albuquerque, New Mexico.ORCID 0000-0002-1862-0959
Donald HaverkampDivision of Cancer Prevention and Control, Centers for Disease Control and Prevention, Albuquerque, New Mexico.
Charles L WigginsNew Mexico Tumor Registry, University of New Mexico Comprehensive Cancer Center, Albuquerque, New Mexico.ORCID 0000-0002-0661-8261
Jeffrey McCollumDivision of Epidemiology and Disease Prevention, Indian Health Service, Rockville, Maryland.
Mary C WhiteDivision of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia.ORCID 0000-0002-9826-3962
Judith S KaurNative American Programs, Mayo Clinic, Jacksonville, Florida.ORCID 0000-0002-8889-6870
David K EspeyOffice of the Director, Centers for Disease Control and Prevention, Albuquerque, New Mexico.
Centers for Disease Control and Prevention · UGCenters for Disease Control and Prevention · USIndian Health Service · USJacksonville College · USNew Mexico Cancer Center · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundCancer incidence rates for American Indian and Alaska Native (AI/AN) populations vary by geographic region in the United States. The purpose of this study is to examine cancer incidence rates and trends in the AI/AN population compared with the non-Hispanic white population in the United States for the years 2010 to 2015.

methodsCases diagnosed during 2010 to 2015 were identified from population-based cancer registries and linked with the Indian Health Service (IHS) patient registration databases to describe cancer incidence rates in non-Hispanic AI/AN persons compared with non-Hispanic whites (whites) living in IHS purchased/referred care delivery area counties. Age-adjusted rates were calculated for the 15 most common cancer sites, expressed per 100,000 per year. Incidence rates are presented overall as well as by region. Trends were estimated using joinpoint regression analyses.

resultsLung and colorectal cancer incidence rates were nearly 20% to 2.5 times higher in AI/AN males and nearly 20% to nearly 3 times higher in AI/AN females compared with whites in the Northern Plains, Southern Plains, Pacific Coast, and Alaska. Cancers of the liver, kidney, and stomach were significantly higher in the AI/AN compared with the white population in all regions. We observed more significant decreases in cancer incidence rates in the white population compared with the AI/AN population.

conclusionsFindings demonstrate the importance of examining cancer disparities between AI/AN and white populations. Disparities have widened for lung, female breast, and liver cancers. IMPACT: These findings highlight opportunities for targeted public health interventions to reduce AI/AN cancer incidence.

Indexed as

American Indian or Alaska NativeHealth Status DisparitiesNeoplasmsRegistriesAdolescentAdultAgedAged, 80 and overChildChild, PreschoolFemaleHumansIncidenceInfantInfant, NewbornMale

Identifiers

PMID31575554
PMCPMC6777852
OpenAlexW2978785728

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.