Evidence map›Paper›PMID 31575081›Full record

ArticleInternational journal of molecular sciences2019

Human Leukocyte Antigen and Red Blood Cells Impact Umbilical Cord Blood CD34

Diana Vanegas, Cristian-Camilo Galindo, Iván-Aurelio Páez-Gutiérrez, Lorena-Xiomara González-Acero, Pavel-Tiberio Medina-Valderrama, Juan-Camilo Lozano, Bernardo Camacho-Rodríguez, Ana-María Perdomo-Arciniegas

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Diana VanegasSpecialized researcher, Cord Blood Bank, Instituto Distrital de Ciencia, Biotecnología e Innovación en Salud. Cra. 32 # 12-81, 111611 Bogotá, Colombia. dmvanegas@idcbis.org.co.
Cristian-Camilo GalindoSpecialized researcher, Cord Blood Bank, Instituto Distrital de Ciencia, Biotecnología e Innovación en Salud. Cra. 32 # 12-81, 111611 Bogotá, Colombia. ccgalindoun@gmail.com.
Iván-Aurelio Páez-GutiérrezSpecialized researcher, Cord Blood Bank, Instituto Distrital de Ciencia, Biotecnología e Innovación en Salud. Cra. 32 # 12-81, 111611 Bogotá, Colombia. ipaez@idcbis.org.co.
Lorena-Xiomara González-AceroSpecialized researcher, Cord Blood Bank, Instituto Distrital de Ciencia, Biotecnología e Innovación en Salud. Cra. 32 # 12-81, 111611 Bogotá, Colombia. lxgonzalez@idcbis.org.co.
Pavel-Tiberio Medina-ValderramaSpecialized researcher, Cord Blood Bank, Instituto Distrital de Ciencia, Biotecnología e Innovación en Salud. Cra. 32 # 12-81, 111611 Bogotá, Colombia. ptmedina@idcbis.org.co.
Juan-Camilo LozanoSpecialized researcher, Cord Blood Bank, Instituto Distrital de Ciencia, Biotecnología e Innovación en Salud. Cra. 32 # 12-81, 111611 Bogotá, Colombia. jclozanoc@unal.edu.co.
Bernardo Camacho-RodríguezDirector, Instituto Distrital de Ciencia, Biotecnología e Innovación en Salud. Cra. 32 # 12-81, 111611 Bogotá, Colombia. bacamacho@idcbis.org.co.
Ana-María Perdomo-ArciniegasScientific leader, Cord Blood Bank, Instituto Distrital de Ciencia, Biotecnología e Innovación en Salud. Cra. 32 # 12-81, 111611 Bogotá, Colombia. amperdomo@idcbis.org.co.

Funding

Sistema General de Regalías. Fondo de CTeI, Colombia. Secretaría Distrital de Salud, Bogotá DC, Colombia. BPIN2016000100035
6 · The paper itself

Abstract

Hematopoietic progenitor cell (HPC) transplantation is a treatment option for malignant and nonmalignant diseases. Umbilical cord blood (UCB) is an important HPC source, mainly for pediatric patients. It has been demonstrated that human leukocyte antigen (HLA) matching and cell dose are the most important features impacting clinical outcomes. However, UCB matching is performed using low resolution HLA typing and it has been demonstrated that the unnoticed mismatches negatively impact the transplant. Since we found differences in CD34

Indexed as

Cell CommunicationAllelesAntigens, CD34Cell SurvivalCord Blood Stem Cell TransplantationCryopreservationErythrocytesFetal BloodHematopoietic Stem CellsHLA AntigensHumansAntigens, CD34HLA Antigenscell viabilityhematopoietic stem cell transplantationhuman leukocyte antigenthawingumbilical cord blood

Identifiers

PMID31575081
PMCPMC6801469

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.