Evidence map›Paper›PMID 31575010›Full record

ArticleMarine drugs2019

Unraveling the Detoxification Mechanism of 2,4-Dichlorophenol by Marine-Derived Mesophotic Symbiotic Fungi Isolated from Marine Invertebrates.

Efstratios Nikolaivits, Andreas Agrafiotis, Aikaterini Termentzi, Kyriaki Machera, Géraldine Le Goff, Pedro Álvarez, Suchana Chavanich, Yehuda Benayahu, Jamal Ouazzani, Nikolas Fokialakis and 1 more

Abstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Marine-derived fungi as biocatalysts.Frontiers in microbiology · 2023
    Review
  4. Naturally Occurring Organohalogen Compounds-A Comprehensive Review.Progress in the chemistry of organic natural products · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Draft Genome Sequence of aMicrobiology resource announcements · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Efstratios NikolaivitsIndustrial Biotechnology & Biocatalysis Group, Biotechnology Laboratory, School of Chemical Engineering, National Technical University of Athens, 15780 Athens, Greece. snikolai@central.ntua.gr.ORCID 0000-0002-8022-9272
Andreas AgrafiotisIndustrial Biotechnology & Biocatalysis Group, Biotechnology Laboratory, School of Chemical Engineering, National Technical University of Athens, 15780 Athens, Greece. agrafiotisandreas.vep@gmail.com.
Aikaterini TermentziDepartment of Pesticides Control and Phytopharmacy, Benaki Phytopathological Institute, 14561 Kifissia, Greece. a.termentzi@bpi.gr.
Kyriaki MacheraDepartment of Pesticides Control and Phytopharmacy, Benaki Phytopathological Institute, 14561 Kifissia, Greece. k.machera@bpi.gr.
Géraldine Le GoffInstitut de Chimie des Substances Naturelles, ICSN, Centre National de la Recherche Scientifique CNRS, 91198 Gif sur Yvette, France.
Pedro ÁlvareziMare Natural S.L., 18600 Granada, Spain. pedro.imare@gmail.com.
Suchana ChavanichFaculty of Science, Chulalongkorn University, Bangkok 10330, Thailand. suchana.c@chula.ac.th.
Yehuda BenayahuDepartment of Zoology, Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel. yehudab@tauex.tau.ac.il.
Jamal OuazzaniInstitut de Chimie des Substances Naturelles, ICSN, Centre National de la Recherche Scientifique CNRS, 91198 Gif sur Yvette, France. jamal.ouazzani@cnrs.fr.ORCID 0000-0003-4483-6638
Nikolas FokialakisDivision of Pharmacognosy and Chemistry of Natural Products, Department of Pharmacy, University of Athens, 15771 Athens, Greece. fokialakis@pharm.uoa.gr.ORCID 0000-0001-7028-1870
Evangelos TopakasIndustrial Biotechnology & Biocatalysis Group, Biotechnology Laboratory, School of Chemical Engineering, National Technical University of Athens, 15780 Athens, Greece. vtopakas@chemeng.ntua.gr.ORCID 0000-0003-0078-5904

Funding

Horizon 2020 634674State Scholarships Foundation MIS-5000432
6 · The paper itself

Abstract

Chlorophenols (CPs) are environmental pollutants that are produced through various anthropogenic activities and introduced in the environment. Living organisms, including humans, are exposed to these toxic xenobiotics and suffer from adverse health effects. More specifically, 2,4-dichlorophenol (2,4-DCP) is released in high amounts in the environment and has been listed as a priority pollutant by the US Environmental Protection Agency. Bioremediation has been proposed as a sustainable alternative to conventional remediation methods for the detoxification of phenolic compounds. In this work, we studied the potential of fungal strains isolated as symbionts of marine invertebrates from the underexplored mesophotic coral ecosystems. Hence, the unspecific metabolic pathways of these fungal strains are being explored in the present study, using the powerful analytical capabilities of a UHPLC-HRMS/MS. The newly identified 2,4-DCP metabolites add significantly to the knowledge of the transformation of such pollutants by fungi, since such reports are scarce.

Indexed as

AnimalsAnthozoaAquatic OrganismsBiodegradation, EnvironmentalChlorophenolsEcosystemFungiHumansInvertebratesMetabolic Networks and PathwaysPhenolsSymbiosisWater Pollutants, ChemicalXenobiotics2,4-dichlorophenolChlorophenolsPhenolsWater Pollutants, ChemicalXenobiotics2,4-dichlorophenolbioremediationHRMS/MSinvertebrate symbiontsmarine-derived fungimesophotic zonemetabolite analysis

Identifiers

PMID31575010
PMCPMC6835501

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.