Evidence map›Paper›PMID 31574998›Full record

ArticleVeterinary sciences2019

Reduced FXR Target Gene Expression in Copper-Laden Livers of COMMD1-Deficient Dogs.

Xiaoyan Wu, Hsiaotzu Chien, Monique E van Wolferen, Hedwig S Kruitwagen, Loes A Oosterhoff, Louis C Penning

Open access · goldAbstract read
In one paragraph

Article in Veterinary sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Animal organoids as models for integrated One Health research.One health (Amsterdam, Netherlands) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xiaoyan WuDepartment Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, P.O. BOX 80.154, NL-3508 TD Utrecht, the Netherlands. X.Wu@uu.nl.
Hsiaotzu ChienDepartment Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, P.O. BOX 80.154, NL-3508 TD Utrecht, the Netherlands. vltchien11@gmail.com.
Monique E van WolferenDepartment Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, P.O. BOX 80.154, NL-3508 TD Utrecht, the Netherlands. M.E.vanWolferen@uu.nl.
Hedwig S KruitwagenDepartment Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, P.O. BOX 80.154, NL-3508 TD Utrecht, the Netherlands. H.S.Kruitwagen@uu.nl.
Loes A OosterhoffDepartment Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, P.O. BOX 80.154, NL-3508 TD Utrecht, the Netherlands. L.A.Oosterhoff@uu.nl.
Louis C PenningDepartment Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, P.O. BOX 80.154, NL-3508 TD Utrecht, the Netherlands. L.C.Penning@uu.nl.
Utrecht University · NL

Funding

China Scholarship Council 201407090064Nederlandse Organisatie voor Wetenschappelijk Onderzoek 116004121
6 · The paper itself

Abstract

Wilson's disease (WD), an autosomal recessive disorder, results in copper accumulation in the liver as a consequence of mutations in the gene ATPase copper transporting beta (

Indexed as

Bedlington terrierCOMMD1copper toxicosisnuclear receptor

Identifiers

PMID31574998
PMCPMC6958483
OpenAlexW2976005419

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.