ReviewInternational journal of molecular sciences2019
ILC2 Activation by Protozoan Commensal Microbes.
Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- A gut commensal protozoan determines respiratory disease outcomes by shaping pulmonary immunity.Cell · 2025Article
- NETosis in Parasitic Infections: A Puzzle That Remains Unsolved.International journal of molecular sciences · 2023Review
- The notable global heterogeneity in the distribution of COVID-19 cases and the association with pre-existing parasitic diseases.PLoS neglected tropical diseases · 2022Article
- Regulation of Gastrointestinal Immunity by Metabolites.Nutrients · 2021Review
- Innate Lymphoid Cells and Natural Killer Cells in Bacterial Infections: Function, Dysregulation, and Therapeutic Targets.Frontiers in cellular and infection microbiology · 2021Review
- Tissue-Specific Molecular Markers and Heterogeneity in Type 2 Innate Lymphoid Cells.Frontiers in immunology · 2021Review
- Interrogating the Impact of Intestinal Parasite-Microbiome on Pathogenesis of COVID-19 in Sub-Saharan Africa.Frontiers in microbiology · 2021Article
- Interleukin-25-mediated resistance against intestinal trematodes does not depend on the generation of Th2 responses.Parasites & vectors · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Group 2 innate lymphoid cells (ILC2s) are a member of the ILC family and are involved in protective and pathogenic type 2 responses. Recent research has highlighted their involvement in modulating tissue and immune homeostasis during health and disease and has uncovered critical signaling circuits. While interactions of ILC2s with the bacterial microbiome are rather sparse, other microbial members of our microbiome, including helminths and protozoans, reveal new and exciting mechanisms of tissue regulation by ILC2s. Here we summarize the current field on ILC2 activation by the tissue and immune environment and highlight particularly new intriguing pathways of ILC2 regulation by protozoan commensals in the intestinal tract.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.