Evidence map›Paper›PMID 31574993›Full record

ReviewMolecules (Basel, Switzerland)2019

Nanobiomaterials Used in Cancer Therapy: An Up-To-Date Overview.

Iulia Ioana Lungu, Alexandru Mihai Grumezescu, Adrian Volceanov, Ecaterina Andronescu

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Facile and green synthesis of α-FeScientific reports · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Iulia Ioana LunguFaculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 011061 Bucharest, Romania. iulia.lunguu@gmail.com.
Alexandru Mihai GrumezescuFaculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 011061 Bucharest, Romania. grumezescu@yahoo.com.ORCID 0000-0003-3036-094X
Adrian VolceanovFaculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 011061 Bucharest, Romania. avolceanov@yahoo.co.uk.ORCID 0000-0002-7668-861X
Ecaterina AndronescuFaculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 011061 Bucharest, Romania. ecaterina.andronescu@upb.ro.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The disadvantages that come with traditional cancer treatments, such as chemotherapy and radiotherapy, generated a research shift toward nanotechnology. However, even with the important advancements regarding cancer therapy, there are still serious stepping stones that need to be addressed. The use of both nanotechnology and nanomedicine has generated significant improvements in nano-sized materials development and their use as therapeutic, diagnosis, and imaging agents. The biological barriers that come from the healthy body, as well from the tumorous sites, are important parameters that need to be taken into consideration when designing drug delivery systems. There are several aspects of extreme importance such as the tumor microenvironment and vasculature, the reticuloendothelial system, the blood-brain barrier, the blood-tumor barrier, and the renal system. In order to achieve an effective system for cancer therapy, several characteristics of the nanoparticles have been outlined. Moreover, this review has also focused on the different types of nanoparticles that have been studied over the years as potential candidates for cancer therapy.

Indexed as

Biocompatible MaterialsDrug CarriersDrug Delivery SystemsTheranostic NanomedicineAnimalsAntineoplastic AgentsHumansNanoparticlesNanotechnologyNeoplasmsAntineoplastic AgentsBiocompatible MaterialsDrug Carriersbiological barrierscancer therapydrug deliverynanoparticlestheranostics

Identifiers

PMID31574993
PMCPMC6804091

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.