Evidence map›Paper›PMID 31574228›Full record

ArticleAmerican journal of respiratory and critical care medicine2020

Effects of a Resuscitation Strategy Targeting Peripheral Perfusion Status versus Serum Lactate Levels among Patients with Septic Shock. A Bayesian Reanalysis of the ANDROMEDA-SHOCK Trial.

Fernando G Zampieri, Lucas P Damiani, Jan Bakker, Gustavo A Ospina-Tascón, Ricardo Castro, Alexandre B Cavalcanti, Glenn Hernandez

Registry-linked trialAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in American journal of respiratory and critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06568744 (Fluid Intolerance Signals as Safety Limits to Prevent Fluid-induced Harm During Septic Shock Resuscitation), which is not on this map. Cited by 115 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed, 5 pooled it
15.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06568744 narecruitingnot on this mapstarted 2024, after this paper: background citation

Fluid Intolerance Signals as Safety Limits to Prevent Fluid-induced Harm During Septic Shock Resuscitation

TypeinterventionalSponsorPontificia Universidad Catolica de ChileRan2024 to 2026Enrolled62ConditionsSeptic ShockArmsIntervention resuscitation, Standard of Care resuscitation
3 · Its place in the literature

Who cites it

115 citing papers in PubMed, 5 syntheses or guidelines pooled it, 235 citations in OpenAlex.

  1. Guideline
  2. Pooled it
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  5. Pooled it
  6. Trial
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  13. Article
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  16. Review
  17. Bayesian Thinking in the Intensive Care Unit: From Statistical Theory to Clinical Practice.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026
    Article
  18. Lactate clearance in patients with septic shock: identifying the point of diminishing returns.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2026
    Article
  19. Review
  20. Article

55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 5 countries.

Fernando G ZampieriResearch Institute, HCor-Hospital do Coração, São Paulo, Brazil.ORCID 0000-0001-9315-6386
Lucas P DamianiResearch Institute, HCor-Hospital do Coração, São Paulo, Brazil.
Jan BakkerDepartamento de Medicina Intensiva, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Gustavo A Ospina-TascónDepartment of Intensive Care Medicine, Fundación Valle del Lili, Universidad ICESI, Cali, Colombia.ORCID 0000-0001-9370-3298
Ricardo CastroDepartamento de Medicina Intensiva, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Alexandre B CavalcantiResearch Institute, HCor-Hospital do Coração, São Paulo, Brazil.
Glenn HernandezDepartamento de Medicina Intensiva, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Pontificia Universidad Católica de Chile · CLHospital do Coração · BRD’Or Institute for Research and Education · BRFundación Valle del Lili · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAged, 80 and overBayes TheoremFemaleFluid TherapyHumansLactic AcidMaleMiddle AgedOrgan Dysfunction ScoresPerfusion IndexResuscitationShock, SepticLactic AcidBayesian statisticscapillary refill timelactateseptic shock

Identifiers

PMID31574228
OpenAlexW2985332844

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.