Evidence map›Paper›PMID 31573729›Full record

ArticleInternational journal of clinical practice2020

Why knowing healthy controls matters.

Adriana J Pavletic

Abstract read
In one paragraph

Article in International journal of clinical practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. The Interaction BetweenBrain sciences · 2025
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Adriana J PavleticNational Institute of Mental Health, Office of the Clinical Director, Bethesda, MD, USA.ORCID https://orcid.org/0000-0001-7925-2937

Funding

Psychiatry Consultation Liaison Service ResearchZIAMH002922 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PAO, MARYLAND · 2009 to 2025
$11.5M
Intramural NIH HHS Z99 MH999999Intramural NIH HHS ZIA MH002922NIMH NIH HHS ZIA MH002922-10
6 · The paper itself

Abstract

Although healthy volunteers often serve as controls or primary participants in neuroscience research, they are usually less rigorously screened than patients, which can have far-reaching implications for interpretation of study results. Although this issue has long been recognised, it is rarely discussed in the research literature. This article examines how the rigorous screening and characterisation of healthy volunteers is key for quality research.

Indexed as

Healthy VolunteersBiomedical ResearchControl GroupsFemaleHumansMaleMental DisordersNervous System DiseasesNeurosciencescharacterisationcontrolsHealthy volunteersneuroscience researchscreening

Identifiers

PMID31573729
PMCPMC6980973

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.