ArticleRadiology2019
Opportunities in Interventional and Diagnostic Imaging by Using High-Performance Low-Field-Strength MRI.
Registry-linked trialAbstract read
In one paragraph
Article in Radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05469139 (Assessing Brain Injury Using Portable Magnetic Resonance Imaging in Patients With Extracorporeal Membrane Oxygenation), which is not on this map. Cited by 213 papers, 3 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
213citing papers in PubMed, 3 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assessing Brain Injury Using Portable Magnetic Resonance Imaging in Patients With Extracorporeal Membrane Oxygenation
Who cites it
213 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Longitudinal relaxation rate (Magma (New York, N.Y.) · 2025Pooled it
- Society for Cardiovascular Magnetic Resonance recommendations toward environmentally sustainable cardiovascular magnetic resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025Guideline
- State-of-the-art review of lung imaging in cystic fibrosis with recommendations for pulmonologists and radiologists from the "iMAging managEment of cySTic fibROsis" (MAESTRO) consortium.European respiratory review : an official journal of the European Respiratory Society · 2022Pooled it
- Pulmonary Dysfunction after Pediatric COVID-19.Radiology · 2023Trial
- Feasibility of free-breathing 0.55-T lung MRI for structural and functional characterization in preterm infants with bronchopulmonary dysplasia.Pediatric radiology · 2026Article
- 3D Simultaneous Post-contrast T1/T2 Mapping and Synthetic Multi-Contrast Late Gadolinium Enhancement at 0.55T: Validation in Porcine Myocardial Infarction Model.Investigative radiology · 2026Article
- Variable flip angle T1 mapping for quantitative liver imaging at 0.55 T.Magma (New York, N.Y.) · 2026Article
- Magnetic resonance imaging.Science advances · 2026Review
- Simultaneous 3D structural-functional assessment of pediatric lung using 0.55-T MRI: a feasibility study.Radiology advances · 2026Article
- Ventilation Imaging of the Lung at 0.55T With Continuous Slice Cycling.Magnetic resonance in medicine · 2026Article
- Contemporary 0.55 T MRI for Lung Disease Assessment in Children and Young Adults with Cystic Fibrosis: A Proof-of-Concept Study.Tomography (Ann Arbor, Mich.) · 2026Article
- Dynamic Mode Decomposition (DMD) for Low-Latency Real-Time Cardiac MRI.Magnetic resonance in medicine · 2026Article
- Characterizing chronic obstructive pulmonary disease using quantitative MRI biomarkers.The British journal of radiology · 2026Review
- An evaluation of brain volume and cortical thickness measurement at 0.55 T.Magma (New York, N.Y.) · 2026Article
- Net zero emission MR imaging using a permanent 0.4 T magnet.Magma (New York, N.Y.) · 2026Article
- Feasibility of lung imaging at 0.55T for assessment of interstitial lung disease in patients with pulmonary sarcoidosis.European radiology · 2026Article
- Hybrid learning: a combination of self-supervised and supervised learning for joint MRI reconstruction and denoising in low-field MRI.Physics in medicine and biology · 2026Article
- Contemporary 0.55 T MRI to visualize interstitial lung disease - An exploratory study.European journal of radiology open · 2026Article
- Feasibility of Magnetic Resonance Imaging-Guided Pulmonary Artery Stenting in a Commercial Wide-Bore 0.55-T Scanner.JACC. Basic to translational science · 2026Article
- Optimization of fetal brain MRI at 0.55 T with slice-to-volume reconstruction.Magma (New York, N.Y.) · 2026Article
153 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
24 authors.
Adrienne E Campbell-WashburnFrom the Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (A.E.C.W., R.R., M.C.R., I.B., B.B., D.A.H., M.S.H., T.R., W.P.B., D.R.M., C.M., M.Y.C., R.J.L.); Siemens Healthcare GmbH, Erlangen, Germany (D.G., R.S.); Siemens Medical Solutions Inc, Malvern Pa (W.M., H.B.); Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Building 10, Room 4C-1581, Bethesda, MD 20892-1458 (H.X., P.K., R.S.B.); Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.M.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (A.A.M., E.C.J.); and Laboratory of Functional and Molecular Imaging, Division of Intramural Research, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Md (A.P.K.).ORCID 0000-0002-7169-5693
Rajiv RamasawmyFrom the Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (A.E.C.W., R.R., M.C.R., I.B., B.B., D.A.H., M.S.H., T.R., W.P.B., D.R.M., C.M., M.Y.C., R.J.L.); Siemens Healthcare GmbH, Erlangen, Germany (D.G., R.S.); Siemens Medical Solutions Inc, Malvern Pa (W.M., H.B.); Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Building 10, Room 4C-1581, Bethesda, MD 20892-1458 (H.X., P.K., R.S.B.); Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.M.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (A.A.M., E.C.J.); and Laboratory of Functional and Molecular Imaging, Division of Intramural Research, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Md (A.P.K.).
Matthew C RestivoFrom the Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (A.E.C.W., R.R., M.C.R., I.B., B.B., D.A.H., M.S.H., T.R., W.P.B., D.R.M., C.M., M.Y.C., R.J.L.); Siemens Healthcare GmbH, Erlangen, Germany (D.G., R.S.); Siemens Medical Solutions Inc, Malvern Pa (W.M., H.B.); Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Building 10, Room 4C-1581, Bethesda, MD 20892-1458 (H.X., P.K., R.S.B.); Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.M.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (A.A.M., E.C.J.); and Laboratory of Functional and Molecular Imaging, Division of Intramural Research, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Md (A.P.K.).
Ipshita BhattacharyaFrom the Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (A.E.C.W., R.R., M.C.R., I.B., B.B., D.A.H., M.S.H., T.R., W.P.B., D.R.M., C.M., M.Y.C., R.J.L.); Siemens Healthcare GmbH, Erlangen, Germany (D.G., R.S.); Siemens Medical Solutions Inc, Malvern Pa (W.M., H.B.); Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Building 10, Room 4C-1581, Bethesda, MD 20892-1458 (H.X., P.K., R.S.B.); Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.M.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (A.A.M., E.C.J.); and Laboratory of Functional and Molecular Imaging, Division of Intramural Research, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Md (A.P.K.).ORCID 0000-0003-1976-5372
Burcu BasarFrom the Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (A.E.C.W., R.R., M.C.R., I.B., B.B., D.A.H., M.S.H., T.R., W.P.B., D.R.M., C.M., M.Y.C., R.J.L.); Siemens Healthcare GmbH, Erlangen, Germany (D.G., R.S.); Siemens Medical Solutions Inc, Malvern Pa (W.M., H.B.); Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Building 10, Room 4C-1581, Bethesda, MD 20892-1458 (H.X., P.K., R.S.B.); Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.M.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (A.A.M., E.C.J.); and Laboratory of Functional and Molecular Imaging, Division of Intramural Research, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Md (A.P.K.).
Daniel A HerzkaFrom the Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (A.E.C.W., R.R., M.C.R., I.B., B.B., D.A.H., M.S.H., T.R., W.P.B., D.R.M., C.M., M.Y.C., R.J.L.); Siemens Healthcare GmbH, Erlangen, Germany (D.G., R.S.); Siemens Medical Solutions Inc, Malvern Pa (W.M., H.B.); Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Building 10, Room 4C-1581, Bethesda, MD 20892-1458 (H.X., P.K., R.S.B.); Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.M.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (A.A.M., E.C.J.); and Laboratory of Functional and Molecular Imaging, Division of Intramural Research, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Md (A.P.K.).
Michael S HansenFrom the Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (A.E.C.W., R.R., M.C.R., I.B., B.B., D.A.H., M.S.H., T.R., W.P.B., D.R.M., C.M., M.Y.C., R.J.L.); Siemens Healthcare GmbH, Erlangen, Germany (D.G., R.S.); Siemens Medical Solutions Inc, Malvern Pa (W.M., H.B.); Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Building 10, Room 4C-1581, Bethesda, MD 20892-1458 (H.X., P.K., R.S.B.); Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.M.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (A.A.M., E.C.J.); and Laboratory of Functional and Molecular Imaging, Division of Intramural Research, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Md (A.P.K.).
Toby RogersFrom the Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (A.E.C.W., R.R., M.C.R., I.B., B.B., D.A.H., M.S.H., T.R., W.P.B., D.R.M., C.M., M.Y.C., R.J.L.); Siemens Healthcare GmbH, Erlangen, Germany (D.G., R.S.); Siemens Medical Solutions Inc, Malvern Pa (W.M., H.B.); Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Building 10, Room 4C-1581, Bethesda, MD 20892-1458 (H.X., P.K., R.S.B.); Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.M.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (A.A.M., E.C.J.); and Laboratory of Functional and Molecular Imaging, Division of Intramural Research, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Md (A.P.K.).
W Patricia BandettiniFrom the Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (A.E.C.W., R.R., M.C.R., I.B., B.B., D.A.H., M.S.H., T.R., W.P.B., D.R.M., C.M., M.Y.C., R.J.L.); Siemens Healthcare GmbH, Erlangen, Germany (D.G., R.S.); Siemens Medical Solutions Inc, Malvern Pa (W.M., H.B.); Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Building 10, Room 4C-1581, Bethesda, MD 20892-1458 (H.X., P.K., R.S.B.); Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.M.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (A.A.M., E.C.J.); and Laboratory of Functional and Molecular Imaging, Division of Intramural Research, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Md (A.P.K.).
Delaney R McGuirtFrom the Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (A.E.C.W., R.R., M.C.R., I.B., B.B., D.A.H., M.S.H., T.R., W.P.B., D.R.M., C.M., M.Y.C., R.J.L.); Siemens Healthcare GmbH, Erlangen, Germany (D.G., R.S.); Siemens Medical Solutions Inc, Malvern Pa (W.M., H.B.); Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Building 10, Room 4C-1581, Bethesda, MD 20892-1458 (H.X., P.K., R.S.B.); Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.M.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (A.A.M., E.C.J.); and Laboratory of Functional and Molecular Imaging, Division of Intramural Research, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Md (A.P.K.).
Christine ManciniFrom the Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (A.E.C.W., R.R., M.C.R., I.B., B.B., D.A.H., M.S.H., T.R., W.P.B., D.R.M., C.M., M.Y.C., R.J.L.); Siemens Healthcare GmbH, Erlangen, Germany (D.G., R.S.); Siemens Medical Solutions Inc, Malvern Pa (W.M., H.B.); Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Building 10, Room 4C-1581, Bethesda, MD 20892-1458 (H.X., P.K., R.S.B.); Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.M.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (A.A.M., E.C.J.); and Laboratory of Functional and Molecular Imaging, Division of Intramural Research, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Md (A.P.K.).
David GrodzkiFrom the Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (A.E.C.W., R.R., M.C.R., I.B., B.B., D.A.H., M.S.H., T.R., W.P.B., D.R.M., C.M., M.Y.C., R.J.L.); Siemens Healthcare GmbH, Erlangen, Germany (D.G., R.S.); Siemens Medical Solutions Inc, Malvern Pa (W.M., H.B.); Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Building 10, Room 4C-1581, Bethesda, MD 20892-1458 (H.X., P.K., R.S.B.); Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.M.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (A.A.M., E.C.J.); and Laboratory of Functional and Molecular Imaging, Division of Intramural Research, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Md (A.P.K.).
Rainer SchneiderFrom the Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (A.E.C.W., R.R., M.C.R., I.B., B.B., D.A.H., M.S.H., T.R., W.P.B., D.R.M., C.M., M.Y.C., R.J.L.); Siemens Healthcare GmbH, Erlangen, Germany (D.G., R.S.); Siemens Medical Solutions Inc, Malvern Pa (W.M., H.B.); Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Building 10, Room 4C-1581, Bethesda, MD 20892-1458 (H.X., P.K., R.S.B.); Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.M.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (A.A.M., E.C.J.); and Laboratory of Functional and Molecular Imaging, Division of Intramural Research, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Md (A.P.K.).
Waqas MajeedFrom the Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (A.E.C.W., R.R., M.C.R., I.B., B.B., D.A.H., M.S.H., T.R., W.P.B., D.R.M., C.M., M.Y.C., R.J.L.); Siemens Healthcare GmbH, Erlangen, Germany (D.G., R.S.); Siemens Medical Solutions Inc, Malvern Pa (W.M., H.B.); Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Building 10, Room 4C-1581, Bethesda, MD 20892-1458 (H.X., P.K., R.S.B.); Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.M.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (A.A.M., E.C.J.); and Laboratory of Functional and Molecular Imaging, Division of Intramural Research, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Md (A.P.K.).ORCID 0000-0002-1280-0238
Himanshu BhatFrom the Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (A.E.C.W., R.R., M.C.R., I.B., B.B., D.A.H., M.S.H., T.R., W.P.B., D.R.M., C.M., M.Y.C., R.J.L.); Siemens Healthcare GmbH, Erlangen, Germany (D.G., R.S.); Siemens Medical Solutions Inc, Malvern Pa (W.M., H.B.); Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Building 10, Room 4C-1581, Bethesda, MD 20892-1458 (H.X., P.K., R.S.B.); Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.M.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (A.A.M., E.C.J.); and Laboratory of Functional and Molecular Imaging, Division of Intramural Research, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Md (A.P.K.).
Hui XueFrom the Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (A.E.C.W., R.R., M.C.R., I.B., B.B., D.A.H., M.S.H., T.R., W.P.B., D.R.M., C.M., M.Y.C., R.J.L.); Siemens Healthcare GmbH, Erlangen, Germany (D.G., R.S.); Siemens Medical Solutions Inc, Malvern Pa (W.M., H.B.); Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Building 10, Room 4C-1581, Bethesda, MD 20892-1458 (H.X., P.K., R.S.B.); Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.M.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (A.A.M., E.C.J.); and Laboratory of Functional and Molecular Imaging, Division of Intramural Research, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Md (A.P.K.).ORCID 0000-0002-4561-5530
Joel MossFrom the Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (A.E.C.W., R.R., M.C.R., I.B., B.B., D.A.H., M.S.H., T.R., W.P.B., D.R.M., C.M., M.Y.C., R.J.L.); Siemens Healthcare GmbH, Erlangen, Germany (D.G., R.S.); Siemens Medical Solutions Inc, Malvern Pa (W.M., H.B.); Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Building 10, Room 4C-1581, Bethesda, MD 20892-1458 (H.X., P.K., R.S.B.); Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.M.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (A.A.M., E.C.J.); and Laboratory of Functional and Molecular Imaging, Division of Intramural Research, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Md (A.P.K.).
Ashkan A MalayeriFrom the Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (A.E.C.W., R.R., M.C.R., I.B., B.B., D.A.H., M.S.H., T.R., W.P.B., D.R.M., C.M., M.Y.C., R.J.L.); Siemens Healthcare GmbH, Erlangen, Germany (D.G., R.S.); Siemens Medical Solutions Inc, Malvern Pa (W.M., H.B.); Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Building 10, Room 4C-1581, Bethesda, MD 20892-1458 (H.X., P.K., R.S.B.); Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.M.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (A.A.M., E.C.J.); and Laboratory of Functional and Molecular Imaging, Division of Intramural Research, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Md (A.P.K.).ORCID 0000-0002-4442-7343
Elizabeth C JonesFrom the Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (A.E.C.W., R.R., M.C.R., I.B., B.B., D.A.H., M.S.H., T.R., W.P.B., D.R.M., C.M., M.Y.C., R.J.L.); Siemens Healthcare GmbH, Erlangen, Germany (D.G., R.S.); Siemens Medical Solutions Inc, Malvern Pa (W.M., H.B.); Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Building 10, Room 4C-1581, Bethesda, MD 20892-1458 (H.X., P.K., R.S.B.); Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.M.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (A.A.M., E.C.J.); and Laboratory of Functional and Molecular Imaging, Division of Intramural Research, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Md (A.P.K.).
Alan P KoretskyFrom the Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (A.E.C.W., R.R., M.C.R., I.B., B.B., D.A.H., M.S.H., T.R., W.P.B., D.R.M., C.M., M.Y.C., R.J.L.); Siemens Healthcare GmbH, Erlangen, Germany (D.G., R.S.); Siemens Medical Solutions Inc, Malvern Pa (W.M., H.B.); Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Building 10, Room 4C-1581, Bethesda, MD 20892-1458 (H.X., P.K., R.S.B.); Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.M.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (A.A.M., E.C.J.); and Laboratory of Functional and Molecular Imaging, Division of Intramural Research, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Md (A.P.K.).
Peter KellmanFrom the Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (A.E.C.W., R.R., M.C.R., I.B., B.B., D.A.H., M.S.H., T.R., W.P.B., D.R.M., C.M., M.Y.C., R.J.L.); Siemens Healthcare GmbH, Erlangen, Germany (D.G., R.S.); Siemens Medical Solutions Inc, Malvern Pa (W.M., H.B.); Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Building 10, Room 4C-1581, Bethesda, MD 20892-1458 (H.X., P.K., R.S.B.); Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.M.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (A.A.M., E.C.J.); and Laboratory of Functional and Molecular Imaging, Division of Intramural Research, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Md (A.P.K.).
Marcus Y ChenFrom the Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (A.E.C.W., R.R., M.C.R., I.B., B.B., D.A.H., M.S.H., T.R., W.P.B., D.R.M., C.M., M.Y.C., R.J.L.); Siemens Healthcare GmbH, Erlangen, Germany (D.G., R.S.); Siemens Medical Solutions Inc, Malvern Pa (W.M., H.B.); Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Building 10, Room 4C-1581, Bethesda, MD 20892-1458 (H.X., P.K., R.S.B.); Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.M.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (A.A.M., E.C.J.); and Laboratory of Functional and Molecular Imaging, Division of Intramural Research, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Md (A.P.K.).ORCID 0000-0003-0743-9369
Robert J LedermanFrom the Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (A.E.C.W., R.R., M.C.R., I.B., B.B., D.A.H., M.S.H., T.R., W.P.B., D.R.M., C.M., M.Y.C., R.J.L.); Siemens Healthcare GmbH, Erlangen, Germany (D.G., R.S.); Siemens Medical Solutions Inc, Malvern Pa (W.M., H.B.); Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Building 10, Room 4C-1581, Bethesda, MD 20892-1458 (H.X., P.K., R.S.B.); Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.M.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (A.A.M., E.C.J.); and Laboratory of Functional and Molecular Imaging, Division of Intramural Research, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Md (A.P.K.).
Robert S BalabanFrom the Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (A.E.C.W., R.R., M.C.R., I.B., B.B., D.A.H., M.S.H., T.R., W.P.B., D.R.M., C.M., M.Y.C., R.J.L.); Siemens Healthcare GmbH, Erlangen, Germany (D.G., R.S.); Siemens Medical Solutions Inc, Malvern Pa (W.M., H.B.); Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Building 10, Room 4C-1581, Bethesda, MD 20892-1458 (H.X., P.K., R.S.B.); Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.M.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (A.A.M., E.C.J.); and Laboratory of Functional and Molecular Imaging, Division of Intramural Research, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Md (A.P.K.).
Funding
Therapies enabled-cardiovascular interventional MRIZ01HL005062 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI LEDERMAN, ROBERT J · 2003 to 2008
$6.0MIntramural NIH HHS Z01 HL005062
Abstract
Background Commercial low-field-strength MRI systems are generally not equipped with state-of-the-art MRI hardware, and are not suitable for demanding imaging techniques. An MRI system was developed that combines low field strength (0.55 T) with high-performance imaging technology. Purpose To evaluate applications of a high-performance low-field-strength MRI system, specifically MRI-guided cardiovascular catheterizations with metallic devices, diagnostic imaging in high-susceptibility regions, and efficient image acquisition strategies. Materials and Methods A commercial 1.5-T MRI system was modified to operate at 0.55 T while maintaining high-performance hardware, shielded gradients (45 mT/m; 200 T/m/sec), and advanced imaging methods. MRI was performed between January 2018 and April 2019. T1, T2, and T2* were measured at 0.55 T; relaxivity of exogenous contrast agents was measured; and clinical applications advantageous at low field were evaluated. Results There were 83 0.55-T MRI examinations performed in study participants (45 women; mean age, 34 years ± 13). On average, T1 was 32% shorter, T2 was 26% longer, and T2* was 40% longer at 0.55 T compared with 1.5 T. Nine metallic interventional devices were found to be intrinsically safe at 0.55 T (<1°C heating) and MRI-guided right heart catheterization was performed in seven study participants with commercial metallic guidewires. Compared with 1.5 T, reduced image distortion was shown in lungs, upper airway, cranial sinuses, and intestines because of improved field homogeneity. Oxygen inhalation generated lung signal enhancement of 19% ± 11 (standard deviation) at 0.55 T compared with 7.6% ± 6.3 at 1.5 T (
Indexed as
CatheterizationAdultArtifactsCardiac CatheterizationContrast MediaEquipment DesignFemaleHumansImage EnhancementMagnetic Resonance ImagingMagnetic Resonance Imaging, InterventionalMetalsSignal-To-Noise RatioContrast MediaMetals
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NCT05469139ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.