Evidence map›Paper›PMID 31573350›Full record

GuidelineAmerican journal of respiratory and critical care medicine2019

Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America.

Joshua P Metlay, Grant W Waterer, Ann C Long, Antonio Anzueto, Jan Brozek, Kristina Crothers, Laura A Cooley, Nathan C Dean, Michael J Fine, Scott A Flanders and 5 more

11 registry-linked trialsAbstract readPractice Guideline
In one paragraph

Guideline in American journal of respiratory and critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 11 registered trials, which are not on this map. Cited by 1,927 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,927citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04365582 phase3withdrawnnot on this mapstarted 2020, after this paper: background citation

A Randomized Trial of Efficacy and Safety of an Early OUTpatient Treatment of COVID-19 in Patients With Risk Factor for Poor Outcome: a Strategy to Prevent Hospitalization

TypeinterventionalSponsorFondation Hôpital Saint-JosephRan2020 to 2021Enrolled0ConditionsCOVIDArmsAzithromycin, Hydroxychloroquine, Lopinavir 200Mg/Ritonavir 50Mg Tab
NCT05079620 phase4terminatednot on this mapstarted 2021, after this paper: background citation

Antibiotic Prophylaxis in Critically Ill Patients After Suspected Aspiration

TypeinterventionalSponsorUConn HealthRan2021 to 2024Enrolled5ConditionsAspiration, Aspiration PneumoniaArmsCeftriaxone, Amoxicillin clavulanic acid, Cefepime, Vancomycin, Levofloxacin
NCT05568654 nacompletednot on this mapstarted 2022, after this paper: background citation

Reducing Antimicrobial Overuse Through Targeted Therapy for Patients With Community-Acquired Pneumonia

TypeinterventionalSponsorThe Cleveland ClinicRan2022 to 2026Enrolled28,580ConditionsCommunity-Acquired Pneumonia, Antimicrobial Stewardship, Point-of-Care TestingArmsRapid Diagnostic Testing, Pharmacist-led de-escalation
NCT05833412 unknown statusnot on this mapstarted 2023, after this paper: background citation

Clinical Study to Improve the Quality of Care in Critically Ill Patients With Suspected Sepsis Through Early Molecular Diagnosis .

Typeobservational_patient_registrySponsorAlejandro Rodriguez Oviedo , MDRan2023 to 2024Enrolled120ConditionsSepsis, Molecular DiagnosisArmsSepticyte Rapid ®, FilmArray® blood culture identification (BCID2®)
NCT05975671 narecruitingnot on this mapstarted 2023, after this paper: background citation

Reducing Empiric VAncomycin Use in Pediatric Suspected Sepsis (REVAMP-Sepsis)

TypeinterventionalSponsorChildren's Hospital of PhiladelphiaRan2023 to 2026Enrolled52,500ConditionsSepsis, Sepsis Mrsa, Sepsis Bacteremia, Antimicrobial - Induced NephropathyArmsMultifaceted de-implementation strategy to reduce vancomycin overuse
NCT06238297 narecruitingnot on this mapstarted 2024, after this paper: background citation

Rapid De-escalation of Anti-MRSA Therapy Guided by S. Aureus Nares Screening in Case of Pneumonia (SNAP Study)

TypeinterventionalSponsorUniversity of Bari Aldo MoroRan2024 to 2025Enrolled76ConditionsPneumonia, BacterialArmsMRSA nasal swab based de-escalation
NCT06259110 unknown statusnot on this mapstarted 2024, after this paper: background citation

Revolutionizing Community-Acquired Pneumonia Diagnosis Through Integrating Novel Microbiological Techniques for Enhanced Precision

TypeobservationalSponsorAssiut UniversityRan2024 to 2025Enrolled70ConditionsCommunity-acquired PneumoniaArmsMultiplex PCR
NCT06272994 nacompletednot on this mapstarted 2024, after this paper: background citation

Swab Testing to Optimize Pneumonia Treatment With Empiric Vancomycin (STOP-Vanc)

TypeinterventionalSponsorVanderbilt University Medical CenterRan2024 to 2025Enrolled277ConditionsCommunity-acquired PneumoniaArmsMRSA Nasal Swab PCR
NCT06566898 recruitingnot on this mapstarted 2024, after this paper: background citation

Monitoring of Antimicrobial Resistance Based on Metagenomics Analyses in Pneumonia Patients: a Genomic Epidemiology Study

TypeobservationalSponsorShanghai General Hospital, ChinaRan2024 to 2026Enrolled800ConditionsPneumonia, Next-generation Sequencing, Microbiome, Antimicrobial Resistance
NCT06755814 recruitingnot on this mapstarted 2025, after this paper: background citation

Community-acquired Pneumonia in Immunosuppressed Adult Patients: Observational, Perspective Study, ItAlian ReGistry Of pNeumoniA in immUnocompromised paTients (ARGONAUT)

TypeobservationalSponsorSocieta Italiana di PneumologiaRan2025 to 2028Enrolled1,298ConditionsCommunity Acquired Pneumonia (CAP)
NCT06837402 enrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Epidemiology of Non- Invasive Mechanical Ventilation in Argentina: a Multicenter Observational Study

TypeobservationalSponsorArgentinian Intensive Care SocietyRan2025 to 2026Enrolled246ConditionsRespiration, Artificial, Noninvasive Ventilation, Intensive Care Units
3 · Its place in the literature

Who cites it

1,927 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Pooled it
  5. Swab Testing to Optimize Pneumonia Treatment With Empiric Vancomycin: A Randomized Controlled Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Trial
  6. Trial
  7. Article
  8. Article
  9. Management of pneumonia by the emergency radiologist.European journal of radiology open · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Rapid diagnosis ofExperimental and therapeutic medicine · 2026
    Article
  15. Article
  16. Article
  17. Observational
  18. Article
  19. Factors Associated with Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2026
    Article
  20. Article

1,867 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Improving clinical outcomes after ICU transfer for acute respiratory failureK23HL128793 · NHLBI · UNIVERSITY OF WASHINGTON · PI JENNERICH, ANN LONG · 2017 to 2021
$941k
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS K23 HL128793
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAmbulatory CareAnti-Bacterial AgentsAntigens, Bacterialbeta-LactamsBlood CultureChlamydophila InfectionsCommunity-Acquired InfectionsCulture TechniquesDrug Therapy, CombinationHaemophilus InfectionsHospitalizationHumansLegionellosisMacrolidesMoraxellaceae InfectionsAnti-Bacterial AgentsAntigens, Bacterialbeta-LactamsMacrolidescommunity-acquired pneumoniapneumonia; patient management

Identifiers

PMID31573350
PMCPMC6812437

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 5 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.