Evidence map›Paper›PMID 31573055›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2020

Lower mortality in an all-comers aortic stenosis population treated with TAVI in comparison to SAVR.

Helge Möllmann, Oliver Husser, Johannes Blumenstein, Christoph Liebetrau, Oliver Dörr, Won-Keun Kim, Holger Nef, Christian Tesche, Christian W Hamm, Albrecht Elsässer and 2 more

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In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Transcatheter or surgical aortic valve implantation in chronic dialysis patients: a German Aortic Valve Registry analysis.Clinical research in cardiology : official journal of the German Cardiac Society · 2021
    Trial
  2. Incidence and trends of patient MACE outcomes after Transcatheter Aortic Valve Implantation (TAVI): analysis by age and sex.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2026
    Article
  3. Transcatheter-based aortic valve replacement vs. isolated surgical aortic valve replacement in 2020.Clinical research in cardiology : official journal of the German Cardiac Society · 2022
    Article
  4. Article
  5. Aortic valve replacement in Germany in 2019.Clinical research in cardiology : official journal of the German Cardiac Society · 2021
    Article
  6. Metabolomic profiling of patients with high gradient aortic stenosis undergoing transcatheter aortic valve replacement.Clinical research in cardiology : official journal of the German Cardiac Society · 2021
    Article
  7. Machine learning-based risk prediction of intrahospital clinical outcomes in patients undergoing TAVI.Clinical research in cardiology : official journal of the German Cardiac Society · 2021
    Article
  8. European heart health survey 2019.Clinical cardiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Helge MöllmannDepartment of Internal Medicine, St. Johannes-Hospital Dortmund, Medizinische Klinik 1; Johannesstrasse 9-17, 44137, Dortmund, Germany. moellman@me.com.
Oliver HusserDepartment of Internal Medicine, St. Johannes-Hospital Dortmund, Medizinische Klinik 1; Johannesstrasse 9-17, 44137, Dortmund, Germany.
Johannes BlumensteinDepartment of Internal Medicine, St. Johannes-Hospital Dortmund, Medizinische Klinik 1; Johannesstrasse 9-17, 44137, Dortmund, Germany.
Christoph LiebetrauDepartment of Cardiology, Kerckhoff Heart and Thorax Center, Bad Nauheim, Germany.
Oliver DörrDepartment of Cardiology and Angiology, Medical Clinic I, University of Giessen, Giessen, Germany.
Won-Keun KimDepartment of Cardiology, Kerckhoff Heart and Thorax Center, Bad Nauheim, Germany.
Holger NefDepartment of Cardiology and Angiology, Medical Clinic I, University of Giessen, Giessen, Germany.
Christian TescheDepartment of Internal Medicine, St. Johannes-Hospital Dortmund, Medizinische Klinik 1; Johannesstrasse 9-17, 44137, Dortmund, Germany.
Christian W HammDepartment of Cardiology, Kerckhoff Heart and Thorax Center, Bad Nauheim, Germany.
Albrecht ElsässerDepartment of Cardiology, Klinikum Oldenburg, Oldenburg, Germany.
Stephan AchenbachMedizinische Klinik 2, Friedrich Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.
Luise GaedeMedizinische Klinik 2, Friedrich Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.
St.-Johannes-Hospital Dortmund · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEKerckhoff Klinik · DEUniversity of Giessen · DEKlinikum Oldenburg · DEUniversitätsklinikum Gießen und Marburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWithin the last years TAVI-especially transfemoral/transvascular TAVI-has proven to be a valuable therapeutic option for most patients suffering from AS. Here, we present the outcome of a complete dataset of all patients undergoing aortic valve replacement in Germany in 2018.

methodsThe data of all aortic valve procedures performed in Germany in 2018 derive from the mandatory nationwide quality control program. Patients were stratified with a new version of the German Aortic valve score (AKL Score) divided in different risk stratification depending on the treatment with either a catheter based (TV-TAVI) or surgical (iSAVR) approach. In-hospital outcomes have been compared between the two approaches.

results19,317 transvascular (TV)-TAVI procedures were carried out. In contrast to this steady growth, the number of iSAVR andtransapical (TA) -TAVI procedures declined. In-hospital mortality after TV-TAVI (2.5%) was lower when compared to iSAVR (3.1%) as well as TA-TAVI (5.7%) in-hospital mortality after TV-TAVI was significantly lowest (Fig. 2) with an in-hospital mortality rate of 2.5%. TV-TAVI was the only approach with an observed vs. expected mortality ratio < 1 according to the used risk prediction model.

conclusionTV-TAVI is more often performed and shows lower in-hospital mortality than iSAVR. TV-TAVI has replaced iSAVR as the gold-standard concerning in-hospital outcome in aortic stenosis management.

Indexed as

AgedAortic Valve StenosisFemaleGermanyHospital MortalityHumansMalePostoperative ComplicationsTranscatheter Aortic Valve ReplacementTreatment OutcomeMortalityReal-worldRegistrySAVRTAVITAVR

Identifiers

PMID31573055
OpenAlexW2978104914

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.