SynthesisAmerican journal of epidemiology2020
The Longitudinal Associations of Perceived Neighborhood Disorder and Lack of Social Cohesion With Depression Among Adults Aged 50 Years or Older: An Individual-Participant-Data Meta-Analysis From 16 High-Income Countries.
Synthesis in American journal of epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- A systematic review on the associations between built environment and mental health among older people.Frontiers in public health · 2025Pooled it
- Involuntary Retirement and Depression Among Adults: A Systematic Review and Meta-Analysis of Longitudinal Studies.Frontiers in psychiatry · 2022Pooled it
- Assessing biological pathways in the longitudinal association between neighborhood environment and depressive symptoms.Journal of affective disorders · 2026Article
- Social cohesion, social capital and mental health: current evidence and future research directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026Article
- The Impact of Neighbours and Neighbourhoods on Major Depressive Disorders in Adults.Journal of urban health : bulletin of the New York Academy of Medicine · 2026Article
- Late-Onset Depression in an Aging World: A Multidimensional Perspective on Risks, Mechanisms, and Treatment.Geriatrics (Basel, Switzerland) · 2026Review
- Improvements to the living environment and mental health among older adults: an empirical study based on the Chinese experience.Frontiers in public health · 2026Article
- The Double Burden of Isolation and Unemployment: Suicide Risk in Structurally Vulnerable Populations in Japan-A Case Study of Akita Prefecture (2018-2022).International journal of environmental research and public health · 2025Article
- Article
- Associations between area deprivation and mental health by household income among cancer caregivers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Neighborhood Social and Physical Environment and Cognitive Function Among Brazilian Adults Aged 50.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- County Incarceration Rate and Stroke Death: A Cross-Sectional Study of the Influence of Physical Environment, Health Care Access, and Community Mental Distress.Journal of the American Heart Association · 2025Article
- Assessing Neighborhood Characteristics and Their Association with Prenatal Maternal Stress, Depressive Symptoms, and Well-Being in Eight Culturally Diverse Cities: A Cross-Sectional Study.International journal of environmental research and public health · 2025Article
- Depressive symptoms during the transition to adolescence: Left hippocampal volume as a marker of social context sensitivity.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Neighborhood poverty and hopelessness in older adults: The mediating role of perceived neighborhood disorder.PloS one · 2024Article
- Perceived social cohesion and depressive symptoms among internal migrants in China: The mediating role of social adaptation.Frontiers in public health · 2023Article
- The effects of neighbourhood social cohesion on preventing depression and anxiety among adolescents and young adults: rapid review.BJPsych open · 2022Review
- Social Determinants of Health and Depression among African American Adults: A Scoping Review of Current Research.International journal of environmental research and public health · 2022Article
- Psychological Distress During the Retirement Transition and the Role of Psychosocial Working Conditions and Social Living Environment.The journals of gerontology. Series B, Psychological sciences and social sciences · 2022Article
- How Is Connectedness With Nature Linked to Life Satisfaction or Depression Among Chinese People Living in Rural Low-Income Households? A Serial Mediation Model.Frontiers in public health · 2022Article
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Although residential environment might be an important predictor of depression among older adults, systematic reviews point to a lack of longitudinal investigations, and the generalizability of the findings is limited to a few countries. We used longitudinal data collected between 2012 and 2017 in 3 surveys including 15 European countries and the United States and comprising 32,531 adults aged 50 years or older. The risk of depression according to perceived neighborhood disorder and lack of social cohesion was estimated using 2-stage individual-participant-data meta-analysis; country-specific parameters were analyzed by meta-regression. We conducted additional analyses on retired individuals. Neighborhood disorder (odds ratio (OR) = 1.25) and lack of social cohesion (OR = 1.76) were significantly associated with depression in the fully adjusted models. In retirement, the risk of depression was even higher (neighborhood disorder: OR = 1.35; lack of social cohesion: OR = 1.93). Heterogeneity across countries was low and was significantly reduced by the addition of country-level data on income inequality and population density. Perceived neighborhood problems increased the overall risk of depression among adults aged 50 years or older. Policies, especially in countries with stronger links between neighborhood and depression, should focus on improving the physical environment and supporting social ties in communities, which can reduce depression and contribute to healthy aging.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.