Evidence map›Paper›PMID 31572864›Full record

ArticleACS omega2019

Chemical Genomic Profiling Unveils the in Vitro and in Vivo Antiplasmodial Mechanism of Açaí (

Letícia T Ferreira, Vinícius P Venancio, Taila Kawano, Lailah C C Abrão, Tatyana A Tavella, Ludimila D Almeida, Gabriel S Pires, Elizabeth Bilsland, Per Sunnerhagen, Luciana Azevedo and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Açaí (Nutrients · 2023
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. The Use ofBiomolecules · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Letícia T FerreiraLaboratory of Tropical Diseases-Prof. Dr. Luiz Jacintho da Silva, Department of Genetics, Evolution, Microbiology and Immunology and Synthetic Biology Laboratory, Department of Structural and Functional Biology, Institute of Biology, University of Campinas-UNICAMP, Campinas, SP 13083-970, Brazil.
Vinícius P VenancioDepartment of Nutrition and Food Science, Texas A&M University, College Station, Texas 77843, United States.
Taila KawanoDepartment of Nutrition and Food Science, Texas A&M University, College Station, Texas 77843, United States.
Lailah C C AbrãoDepartment of Nutrition and Food Science, Texas A&M University, College Station, Texas 77843, United States.
Tatyana A TavellaLaboratory of Tropical Diseases-Prof. Dr. Luiz Jacintho da Silva, Department of Genetics, Evolution, Microbiology and Immunology and Synthetic Biology Laboratory, Department of Structural and Functional Biology, Institute of Biology, University of Campinas-UNICAMP, Campinas, SP 13083-970, Brazil.
Ludimila D AlmeidaLaboratory of Tropical Diseases-Prof. Dr. Luiz Jacintho da Silva, Department of Genetics, Evolution, Microbiology and Immunology and Synthetic Biology Laboratory, Department of Structural and Functional Biology, Institute of Biology, University of Campinas-UNICAMP, Campinas, SP 13083-970, Brazil.
Gabriel S PiresLaboratory of Tropical Diseases-Prof. Dr. Luiz Jacintho da Silva, Department of Genetics, Evolution, Microbiology and Immunology and Synthetic Biology Laboratory, Department of Structural and Functional Biology, Institute of Biology, University of Campinas-UNICAMP, Campinas, SP 13083-970, Brazil.
Elizabeth BilslandLaboratory of Tropical Diseases-Prof. Dr. Luiz Jacintho da Silva, Department of Genetics, Evolution, Microbiology and Immunology and Synthetic Biology Laboratory, Department of Structural and Functional Biology, Institute of Biology, University of Campinas-UNICAMP, Campinas, SP 13083-970, Brazil.
Per SunnerhagenDepartment of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg SE-405 30, Sweden.
Luciana AzevedoLaboratory of Nutritional and Toxicological Analysis in Vivo-LANTIN, Faculty of Nutrition, Federal University of Alfenas, Alfenas, MG, Brazil.
Stephen T TalcottDepartment of Nutrition and Food Science, Texas A&M University, College Station, Texas 77843, United States.
Susanne U Mertens-TalcottDepartment of Nutrition and Food Science, Texas A&M University, College Station, Texas 77843, United States.
Fabio T M CostaLaboratory of Tropical Diseases-Prof. Dr. Luiz Jacintho da Silva, Department of Genetics, Evolution, Microbiology and Immunology and Synthetic Biology Laboratory, Department of Structural and Functional Biology, Institute of Biology, University of Campinas-UNICAMP, Campinas, SP 13083-970, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malaria remains a major detrimental parasitic disease in the developing world, with more than 200 million cases annually. Widespread drug-resistant parasite strains push for the development of novel antimalarial drugs. Plant-derived natural products are key sources of antimalarial molecules.

Identifiers

PMID31572864
PMCPMC6761757

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.