Evidence map›Paper›PMID 31572793›Full record

ArticleTomography (Ann Arbor, Mich.)2019

Test-Retest Performance of a 1-Hour Multiparametric MR Image Acquisition Pipeline With Orthotopic Triple-Negative Breast Cancer Patient-Derived Tumor Xenografts.

Xia Ge, James D Quirk, John A Engelbach, G Larry Bretthorst, Shunqiang Li, Kooresh I Shoghi, Joel R Garbow, Joseph J H Ackerman

Abstract read
In one paragraph

Article in Tomography (Ann Arbor, Mich.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xia GeDepartments of Radiology.
James D QuirkDepartments of Radiology.
John A EngelbachDepartments of Radiology.
G Larry BretthorstDepartments of Radiology.
Shunqiang LiInternal Medicine, and.
Kooresh I ShoghiDepartments of Radiology.
Joel R GarbowDepartments of Radiology.
Joseph J H AckermanDepartments of Radiology.

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI AIMEE S JAMES · 2001 to 2026
$128.0M
WASHINGTON UNIVERSITY CO-CLINICAL IMAGING RESEARCH RESOURCEU24CA209837 · NCI · WASHINGTON UNIVERSITY · PI Li Ding, Shunqiang Li · 2017 to 2026
$6.3M
NCI NIH HHS P30 CA091842NCI NIH HHS U24 CA209837
6 · The paper itself

Abstract

Preclinical imaging is critical in the development of translational strategies to detect diseases and monitor response to therapy. The National Cancer Institute Co-Clinical Imaging Resource Program was launched, in part, to develop best practices in preclinical imaging. In this context, the objective of this work was to develop a 1-hour, multiparametric magnetic resonance image-acquisition pipeline with triple-negative breast cancer patient-derived xenografts (PDXs). The 1-hour, image-acquisition pipeline includes T1- and T2-weighted scans, quantitative T1, T2, and apparent diffusion coefficient (ADC) parameter maps, and dynamic contrast-enhanced (DCE) time-course images. Quality-control measures used phantoms. The triple-negative breast cancer PDXs used for this study averaged 174 ± 73 μL in volume, with region of interest-averaged T1, T2, and ADC values of 1.9 ± 0.2 seconds, 62 ± 3 milliseconds, and 0.71 ± 0.06 μm

Indexed as

Contrast MediaAnimalsBreast NeoplasmsDiffusion Magnetic Resonance ImagingDisease Models, AnimalFemaleHeterograftsHumansMiceMice, Inbred StrainsMultiparametric Magnetic Resonance ImagingPhantoms, ImagingRadiographic Image EnhancementRandom AllocationTask Performance and AnalysisTriple Negative Breast NeoplasmsContrast MediaADCDCEmouseMRImultiparametric MRIPDXpreclinicalsmall animalT1T2Test–retestTNBC

Identifiers

PMID31572793
PMCPMC6752291

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.