Evidence map›Paper›PMID 31572672›Full record

ArticleFrontiers in oncology2019

Non-invasive Bioluminescence Monitoring of Hepatocellular Carcinoma Therapy in an HCR Mouse Model.

Zhu Zhao, Juji Dai, Yan Yu, Qian Zhang, Sai Liu, Guanmeng Huang, Zheng Zhang, Tianke Chen, Rulu Pan, Liting Lu and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Zhu ZhaoSchool of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China.
Juji DaiSchool of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China.
Yan YuSchool of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China.
Qian ZhangSchool of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China.
Sai LiuSchool of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China.
Guanmeng HuangSchool of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China.
Zheng ZhangSchool of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China.
Tianke ChenSchool of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China.
Rulu PanSchool of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China.
Liting LuSchool of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China.
Wenyi ZhangSchool of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China.
Wanqin LiaoSchool of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China.
Xincheng LuSchool of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China.
Wenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Animal models play crucial roles in the development of anticancer therapeutics. The ability to quickly assess the localized primary hepatocellular carcinoma (HCC) status in a non-invasive manner would significantly improve the effectiveness of anti-HCC therapeutic studies. However, to date, animal models with this advantage are extremely scarce. In this study, we developed a novel animal model for the fast assessment of drug efficacy against primary HCC

Indexed as

animal modelbioluminescence imagingdrug efficacy evaluationhepatocarcinogenesis reporter mousehepatocellular carcinoma

Identifiers

PMID31572672
PMCPMC6749040
OpenAlexW2969715220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.