Evidence map›Paper›PMID 31572565›Full record

ArticleNano research2019

Color-coded perfluorocarbon nanodroplets for multiplexed ultrasound and Photoacoustic imaging.

Daniela Y Santiesteban, Kristina A Hallam, Steven K Yarmoska, Stanislav Y Emelianov

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nano research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Daniela Y Santiesteban *Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA.
Kristina A Hallam *Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA.
Steven K YarmoskaWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA.
Stanislav Y EmelianovWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA.

Funding

Acoustic Imaging of Sentinel Node Metastasis using Plasmonic NanosensorsR01EB008101 · NIBIB · UNIVERSITY OF TEXAS AT AUSTIN · PI EMELIANOV, STANISLAV Y, SOKOLOV, KONSTANTIN V · 2007 to 2015
$3.6M
Functional, cellular, and molecular imaging and therapy monitoring using ultrasouR01CA158598 · NCI · UNIVERSITY OF TEXAS AT AUSTIN · PI EMELIANOV, STANISLAV Y, ESTEVA, FRANCISCO J · 2012 to 2018
$2.8M
Comprehensive Training Program in Imaging Science and InformaticsT32EB007507 · NIBIB · UNIVERSITY OF TEXAS AT AUSTIN · PI MARKEY, MIA K, RYLANDER, HENRY GRADY · 2009 to 2024
$2.7M
Molecular photothermal therapy of cancer using targeted metal nanoparticlesR01CA149740 · NCI · UNIVERSITY OF TEXAS AT AUSTIN · PI EMELIANOV, STANISLAV Y · 2010 to 2014
$1.6M
Ultrasound-Guided Molecular Photoacoustic Imaging of BrainR21NS102860 · NINDS · GEORGIA INSTITUTE OF TECHNOLOGY · PI EMELIANOV, STANISLAV Y · 2017 to 2018
$413k
Perfluorocarbon Nanodroplets for the Detection and Treatment of Nodal MetastasesF30CA216939 · NCI · EMORY UNIVERSITY · PI YARMOSKA, STEVEN KARL · 2017 to 2021
$250k
NCI NIH HHS F30 CA216939NCI NIH HHS R01 CA149740NCI NIH HHS R01 CA158598NIBIB NIH HHS R01 EB008101NIBIB NIH HHS T32 EB007507NINDS NIH HHS R21 NS102860
6 · The paper itself

Abstract

Laser-activated perfluorocarbon nanodroplets are an emerging class of phase change, dual-contrast agents that can be utilized in ultrasound and photoacoustic imaging. Through the ability to differentiate subpopulations of nanodroplets via laser activation at different wavelengths of near-infrared light, optically-triggered color-coded perfluorocarbon nanodroplets present themselves as an attractive tool for multiplexed ultrasound and photoacoustic imaging. In particular, laser-activated droplets can be used to provide quantitative spatiotemporal information regarding distinct biological targets, allowing for their potential use in a wide range of diagnos tic and therapeutic applications. In the work presented, laser-activated color-coded perfluorocarbon nanodroplets are synthesized to selectively respond to laser irradiation at corresponding wavelengths. The dynamic ultrasound and photoacoustic signals produced by laser-activated perfluorocarbon nanodroplets are evaluated

Indexed as

molecular targetsmultiplexed imagingperfluorocarbon nanodropletsphotoacoustic imagingultrasound imaging

Identifiers

PMID31572565
PMCPMC6768563

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.