ArticleArchives of medical science : AMS2019
Study of the mechanism of anti-ulcer effects of virgin coconut oil on gastric ulcer-induced rat model.
Article in Archives of medical science : AMS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Pharmacological activities and phytochemical evaluation of coconut crude oil and upon exposure to ozone.AMB Express · 2025Article
- Gastroprotective Effect of Hexanic Extract ofPlants (Basel, Switzerland) · 2024Article
- Isolation, Structural Characteristics Analysis of aMolecules (Basel, Switzerland) · 2023Article
- LC-ESI-MS phenolic contents assessment, antioxidant, and protective ability ofToxicology research · 2023Article
- Integrated serum pharmacochemistry and investigation of the anti-gastric ulcer effect of Zuojin pill in rats induced by ethanol.Pharmaceutical biology · 2022Article
- An accidental emamectin benzoate poisoning in child: A case report.Clinical case reports · 2022Article
- The Protective Effect of Polysaccharide SAFP fromFoods (Basel, Switzerland) · 2022Article
- Gastroprotective Effect of Polypeptide-K Isolated fromEvidence-based complementary and alternative medicine : eCAM · 2022Article
- Protective and therapeutic effects of the flavonoid "pinocembrin" in indomethacin-induced acute gastric ulcer in rats: impact of anti-oxidant, anti-inflammatory, and anti-apoptotic mechanisms.Naunyn-Schmiedeberg's archives of pharmacology · 2021Article
- Royal jelly attenuates gastric mucosal injury in a rat ethanol-induced gastric injury model.Molecular biology reports · 2020Article
- Optimization of Thymoquinone-Loaded Coconut Oil Nanostructured Lipid Carriers for the Management of Ethanol-Induced Ulcer.AAPS PharmSciTech · 2020Article
- Effects of melatonin on ovarian reserve in cigarette smoking: an experimental study.Archives of medical science : AMS · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThis study aims to evaluate the gastro-protective effects of virgin coconut oil (VCO) on different ulcer models as compared to the standard drug (omeprazole). MATERIAL AND
methodsThree groups of rats (6 rats per group for each ulcer model) were pre-treated with distilled water for the negative control group, 30 mg/kg of omeprazole for the positive control group and VCO (2 ml per rat) for the treatment group. Animals were pre-treated for 7 days and ulcers were induced with cold restraint stress, piroxicam, ethanol and pylorus ligation. On day eight, animals were sacrificed and ulcer scores were determined based on macroscopic evaluation. The gastric volume, pH, total acidity and mucus content were measured in the pylorus-ligated model. The levels of antioxidants were determined from the gastric tissue homogenates.
resultsVirgin coconut oil significantly (
conclusionsVirgin coconut oil shows a possible association with antioxidant properties to control the regulation of prostaglandin synthesis and protect against reactive oxygen species damage.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.