Evidence map›Paper›PMID 31572465›Full record

ArticleArchives of medical science : AMS2019

Association of retinol binding protein-4, cystatin C, homocysteine and high-sensitivity C-reactive protein levels in patients with newly diagnosed type 2 diabetes mellitus.

Yun-Sheng Wang, Jun Ye, Xiao Yang, Gui-Ping Zhang, Yong-Hong Cao, Rong Zhang, Wu Dai, Qiu Zhang

Open access · goldAbstract read
In one paragraph

Article in Archives of medical science : AMS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yun-Sheng WangDepartment of Endocrinology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Jun YeDepartment of Endocrinology, the Second Hospital of Hefei City, Hefei, Anhui, China.
Xiao YangDepartment of Ultrasonography, the Second Hospital of Hefei City, Hefei, Anhui, China.
Gui-Ping ZhangDepartment of Ultrasonography, the Second Hospital of Hefei City, Hefei, Anhui, China.
Yong-Hong CaoDepartment of Endocrinology, the Second Hospital of Hefei City, Hefei, Anhui, China.
Rong ZhangDepartment of Endocrinology, the Second Hospital of Hefei City, Hefei, Anhui, China.
Wu DaiDepartment of Endocrinology, the Second Hospital of Hefei City, Hefei, Anhui, China.
Qiu ZhangDepartment of Endocrinology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Third People's Hospital of Hefei · CNFirst Affiliated Hospital of Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTo investigate the serum retinol binding protein (RBP)-4, cystatin C (Cys C), homocysteine (HCY) and high-sensitivity C-reactive protein (hs-CRP) levels in newly diagnosed type 2 diabetes mellitus (NT2DM) patients, prediabetes mellitus (PDM) subjects and normal controls, as well as their correlation with clinical and laboratory indexes, such as blood pressure and lipoprotein. MATERIAL AND

methodsA total of 242 subjects, including 141 NT2DM patients, 48 PDM subjects and 53 healthy controls, were recruited in the present study. Serum RBP-4, Cys C and hs-CRP concentrations were measured by enzyme-linked immunosorbent assay (ELISA). HCY concentration was determined by the chemical luminescence method.

resultsThere were significant differences in Cys C and hs-CRP among NT2DM patients, PDM subjects and normal controls. In comparison to controls, there were significantly elevated Cys C and hs-CRP levels in PDM (both

conclusionsAberrant Cys C expression and its clinical associations in NT2DM suggest their important role in this disease.

Indexed as

cystatin Chigh-sensitivity C-reactive proteinhomocysteineretinol binding protein-4type 2 diabetes mellitus

Identifiers

PMID31572465
PMCPMC6764307
OpenAlexW2901793342

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.