Evidence map›Paper›PMID 31572384›Full record

ReviewFrontiers in immunology2019

Antibiotic Treatment Protocols and Germ-Free Mouse Models in Vascular Research.

Franziska Bayer, Stefanie Ascher, Giulia Pontarollo, Christoph Reinhardt

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Gut Microbiota and the Microvasculature.Cold Spring Harbor perspectives in medicine · 2023
    Review
  10. Sterility testing of germ-free mouse colonies.Frontiers in immunology · 2023
    Review
  11. Article
  12. Review
  13. Article
  14. Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. The microbiome and rodent models of immune mediated diseases.Mammalian genome : official journal of the International Mammalian Genome Society · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Franziska BayerCenter for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg University Mainz, Mainz, Germany.
Stefanie AscherCenter for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg University Mainz, Mainz, Germany.
Giulia PontarolloCenter for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg University Mainz, Mainz, Germany.
Christoph ReinhardtCenter for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg University Mainz, Mainz, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microbiota influence host vascular physiology locally in the intestine, but also evoke remote effects that impact distant organ functions. Amongst others, the microbiota affect intestinal vascular remodeling, lymphatic development, cardiac output and vascular function, myelopoiesis, prothrombotic platelet function, and immunovigilance of the host. Experimentally, host-microbiota interactions are investigated by working with animals devoid of symbiotic bacteria, i.e., by the decimation of gut commensals by antibiotic administration, or by taking advantage of germ-free mouse isolator technology. Remarkably, some of the vascular effects that were unraveled following antibiotic treatment were not observed in the germ-free animal models and

Indexed as

Germ-Free LifeAnimalsAnti-Bacterial AgentsBlood CoagulationBlood PlateletsCardiovascular SystemMiceMyeloid CellsAnti-Bacterial Agentsantibioticsgerm-free mouse modelsmicrobiotaplateletsthrombosisvascular function

Identifiers

PMID31572384
PMCPMC6751252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.