Evidence map›Paper›PMID 31572357›Full record

ArticleFrontiers in immunology2019

Systemic and Intra-Nodal Activation of NK Cells After Rituximab Monotherapy for Follicular Lymphoma.

Monika Enqvist, Benedikt Jacobs, Henna R Junlén, Marie Schaffer, Christopher M Melén, Danielle Friberg, Björn Engelbrekt Wahlin, Karl-Johan Malmberg

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. Addition of Ianalumab (VAY736) to Ibrutinib in Patients with Chronic Lymphocytic Leukemia on Ibrutinib Therapy: Results from a Phase Ib Study.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025
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  10. Unleashing the power of NK cells in anticancer immunotherapy.Journal of molecular medicine (Berlin, Germany) · 2022
    Review
  11. A Hot Topic: Cancer Immunotherapy and Natural Killer Cells.International journal of molecular sciences · 2022
    Review
  12. Phase I Trial of N-803, an IL15 Receptor Agonist, with Rituximab in Patients with Indolent Non-Hodgkin Lymphoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2021
    Article
  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Monika EnqvistDepartment of Medicine, Center for Infectious Medicine, Huddinge, Karolinska Institutet, Stockholm, Sweden.
Benedikt JacobsK.G. Jebsen Center for Cancer Immunotherapy, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Henna R JunlénDivision of Hematology, Department of Medicine, Huddinge, Karolinska Institutet, Stockholm, Sweden.
Marie SchafferDepartment of Medicine, Center for Infectious Medicine, Huddinge, Karolinska Institutet, Stockholm, Sweden.
Christopher M MelénCenter for Hematology, Karolinska University Hospital, Stockholm, Sweden.
Danielle FribergDepartment of Oto-Rhino-Laryngology, Karolinska University Hospital and CLINTEC, Karolinska Institutet, Stockholm, Sweden.
Björn Engelbrekt WahlinDivision of Hematology, Department of Medicine, Huddinge, Karolinska Institutet, Stockholm, Sweden.
Karl-Johan MalmbergDepartment of Medicine, Center for Infectious Medicine, Huddinge, Karolinska Institutet, Stockholm, Sweden.
Karolinska Institutet · SEKarolinska University Hospital · SEUniversitätsklinikum Erlangen · DEUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monotherapy with the anti-CD20 monoclonal antibody rituximab can induce complete responses (CR) in patients with follicular lymphoma (FL). Resting FcRγIII

Indexed as

AdultAgedAged, 80 and overAntibodies, MonoclonalAntibody-Dependent Cell CytotoxicityCD57 AntigensGranzymesHumansInterferon-gammaKi-67 AntigenKiller Cells, NaturalLymphocyte ActivationLymphoma, FollicularMiddle AgedNK Cell Lectin-Like Receptor Subfamily CPerforinAntibodies, MonoclonalCD57 AntigensGranzymesInterferon-gammaKi-67 AntigenNK Cell Lectin-Like Receptor Subfamily CPerforinReceptors, IgGReceptors, KIRRituximabfollicular lymphoma (FL)ki67killer cell immunoglobin-like receptorNK cellrituximab

Identifiers

PMID31572357
PMCPMC6751265
OpenAlexW2969584355

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.