Evidence map›Paper›PMID 31572301›Full record

ArticleFrontiers in endocrinology2019

Protein Expression of PTTG-1, OCT-4, and KLF-4 in Seminoma: A Pilot Study.

Giuseppe Grande, Domenico Milardi, Maurizio Martini, Tonia Cenci, Gaetano Gulino, Francesca Mancini, Antonio Bianchi, Alfredo Pontecorvi, Francesco Pierconti

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Meta-Analysis of Gene Expressions in Testicular Germ Cell Tumor Histologies.International journal of molecular sciences · 2020
    Pooled it
  2. Article
  3. Overexpression of p75Life (Basel, Switzerland) · 2021
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Giuseppe GrandeDivision of Endocrinology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Domenico MilardiDivision of Endocrinology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Maurizio MartiniDivision of Anatomic Pathology and Histology, School of Medicine, Catholic University of Rome, Rome, Italy.
Tonia CenciDivision of Anatomic Pathology and Histology, School of Medicine, Catholic University of Rome, Rome, Italy.
Gaetano GulinoDepartment of Urology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Francesca ManciniInternational Scientific Institute Paul VI, Rome, Italy.
Antonio BianchiDivision of Endocrinology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Alfredo PontecorviDivision of Endocrinology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Francesco PiercontiDivision of Anatomic Pathology and Histology, School of Medicine, Catholic University of Rome, Rome, Italy.
Agostino Gemelli University Polyclinic · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Seminomas are the most frequent kind of testicular germ cell tumors (TGCTs), accounting for 50% of tumor diagnosis in young men, whereas non-seminomas account for 40% and mixed forms for 10% of cases. It is currently supposed that TGCTs evolve from a pre-invasive stage of carcinoma

Indexed as

infiltrationKLF-4OCT-4PTTG-1seminomatestis cancer

Identifiers

PMID31572301
PMCPMC6749154
OpenAlexW2970502455

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.