Evidence map›Paper›PMID 31572109›Full record

ArticleFrontiers in neuroscience2019

Proceedings of the Sixth Deep Brain Stimulation Think Tank Modulation of Brain Networks and Application of Advanced Neuroimaging, Neurophysiology, and Optogenetics.

Adolfo Ramirez-Zamora, James Giordano, Edward S Boyden, Viviana Gradinaru, Aysegul Gunduz, Philip A Starr, Sameer A Sheth, Cameron C McIntyre, Michael D Fox, Jerrold Vitek and 24 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

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  11. Closed-loop DBS triggered by real-time movement and tremor decoding based on thalamic LFPs for essential tremor.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors at 20 institutions in 1 country.

Adolfo Ramirez-ZamoraDepartment of Neurology, Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
James GiordanoNeuroethics Studies Program, Department of Neurology and Department of Biochemistry, Georgetown University Medical Center, Washington, DC, United States.
Edward S BoydenMedia Laboratory, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, United States.
Viviana GradinaruDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, United States.
Aysegul GunduzDepartment of Neuroscience and Department of Biomedical Engineering and Department of Neurology, Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
Philip A StarrGraduate Program in Neuroscience, Department of Neurological Surgery, Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA, United States.
Sameer A ShethDepartment of Neurological Surgery, Baylor College of Medicine, Houston, TX, United States.
Cameron C McIntyreDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States.
Michael D FoxBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Jerrold VitekDepartment of Neurology, University of Minnesota, Minneapolis, MN, United States.
Vinata Vedam-MaiDepartment of Neurosurgery, Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
Umer AkbarCenter for Neurorestoration and Neurotechnology, Rehabilitation R&D Service, Veterans Affairs Medical Center, Brown Institute for Brain Science, Brown University, Providence, RI, United States.
Leonardo AlmeidaDepartment of Neurology, Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
Helen M Bronte-StewartDepartment of Neurology and Department of Neurological Sciences and Department of Neurosurgery, Stanford University, Stanford, CA, United States.
Helen S MaybergDepartment of Neurology and Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Nader PouratianDepartment of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States.
Aryn H GittisBiological Sciences and Center for Neural Basis of Cognition, Carnegie Mellon University, Pittsburgh, PA, United States.
Annabelle C SingerCoulter Department of Biomedical Engineering, Georgia Institute of Technology, Emory University School of Medicine, Atlanta, GA, United States.
Meaghan C CreedDepartment of Pharmacology, University of Maryland School of Medicine, Baltimore, MD, United States.
Gabriel Lazaro-MunozCenter for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX, United States.
Mark RichardsonCenter for the Neural Basis of Cognition, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Marvin A RossiDepartment of Diagnostic Radiology and Nuclear Medicine, Rush University Medical Center, Chicago, IL, United States.
Leopoldo Cendejas-ZaragozaDepartment of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL, United States.
Pierre-Francois D'HaeseElectrical Engineering, Vanderbilt University, Nashville, TN, United States.
Winston ChiongDepartment of Neurology, University of California, San Francisco, San Francisco, CA, United States.
Ro'ee GilronGraduate Program in Neuroscience, Department of Neurological Surgery, Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA, United States.
Howard ChizeckGraduate Program in Neuroscience, Department of Electrical Engineering, University of Washington, Seattle, WA, United States.
Andrew KoDepartment of Neurological Surgery, University of Washington, Seattle, WA, United States.
Kenneth B BakerMovement Disorders Program, Cleveland Clinic Foundation, Cleveland, OH, United States.
Joost WagenaarDepartment of Neurology, Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA, United States.
Noam HarelCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States.
Wissam DeebDepartment of Neurology, Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
Kelly D FooteDepartment of Neurosurgery, Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
Michael S OkunDepartment of Neurology, Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
University of Florida · USNeurological Surgery · USUniversity of California, San Francisco · USUniversity of Minnesota · USBaylor College of Medicine · USBeth Israel Deaconess Medical Center · USBrown University · USCalifornia Institute of Technology · USCarnegie Mellon University · USCase Western Reserve University · USCenter for the Neural Basis of Cognition · USCleveland Clinic · USGeorgetown University · USIcahn School of Medicine at Mount Sinai · USIllinois Institute of Technology · USMassachusetts Institute of Technology · USRush University Medical Center · USStanford University · USThe Wallace H. Coulter Department of Biomedical Engineering · USUniversity of California, Los Angeles · US

Funding

Pathophysiology-based approaches to deep brain stimulation for Parkinson's diseaseP50NS098573 · NINDS · UNIVERSITY OF MINNESOTA · PI JOHNSON, MATTHEW DOUGLAS · 2016 to 2020
$9.1M
Electrophysiological Biomarkers to Optimize DBS for DepressionUH3NS103550 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MAYBERG, HELEN S, RIVA-POSSE, PATRICIO · 2017 to 2023
$7.7M
Novel Platforms for Systematic Optical Control of Complex Neural Circuits In VivoR01DA029639 · NIDA · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BOYDEN, EDWARD S. · 2010 to 2023
$6.7M
Together: Transforming and Translating Discovery to Improve HealthKL2TR001429 · NCATS · UNIVERSITY OF FLORIDA · PI GUIRGIS, FAHEEM W, LEEUWENBURGH, CHRISTIAAN · 2015 to 2023
$5.5M
Non-Invasive Methods to Drive Neural Activity with Millisecond Precision and to Recruit the Brain’s Immune CellsR01NS109226 · NINDS · GEORGIA INSTITUTE OF TECHNOLOGY · PI Annabelle Catherine Singer · 2018 to 2026
$2.7M
Chronic physiologic and behavior changes induced by novel STN DBS patterns for PDR01NS092730 · NINDS · CLEVELAND CLINIC LERNER COM-CWRU · PI BAKER, KENNETH B · 2016 to 2020
$2.7M
NCATS NIH HHS KL2 TR001429NIDA NIH HHS R01 DA029639NINDS NIH HHS P50 NS098573NINDS NIH HHS R01 NS092730NINDS NIH HHS R01 NS109226NINDS NIH HHS UH3 NS103550
6 · The paper itself

Abstract

The annual deep brain stimulation (DBS) Think Tank aims to create an opportunity for a multidisciplinary discussion in the field of neuromodulation to examine developments, opportunities and challenges in the field. The proceedings of the Sixth Annual Think Tank recapitulate progress in applications of neurotechnology, neurophysiology, and emerging techniques for the treatment of a range of psychiatric and neurological conditions including Parkinson's disease, essential tremor, Tourette syndrome, epilepsy, cognitive disorders, and addiction. Each section of this overview provides insight about the understanding of neuromodulation for specific disease and discusses current challenges and future directions. This year's report addresses key issues in implementing advanced neurophysiological techniques, evolving use of novel modulation techniques to deliver DBS, ans improved neuroimaging techniques. The proceedings also offer insights into the new era of brain network neuromodulation and connectomic DBS to define and target dysfunctional brain networks. The proceedings also focused on innovations in applications and understanding of adaptive DBS (closed-loop systems), the use and applications of optogenetics in the field of neurostimulation and the need to develop databases for DBS indications. Finally, updates on neuroethical, legal, social, and policy issues relevant to DBS research are discussed.

Indexed as

deep brain stimulationepilepsyneuromodulationoptogeneticsParkinson’s diseasetemporal dispersionTourette syndrometremor

Identifiers

PMID31572109
PMCPMC6751331
OpenAlexW2969750682

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.