Evidence map›Paper›PMID 31572049›Full record

ArticleJournal of family & community medicine

Potentially inappropriate medications prescribed for older persons: A study from two teaching hospitals in Southern India.

Arun N Bhatt, Sherin S Paul, Smitha Krishnamoorthy, Basil T Baby, Anna Mathew, Balakrishnan R Nair

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Article in Journal of family & community medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Arun N BhattDepartment of Community Medicine, Malankara Orthodox Syrian Church Medical College, Kolenchery, Kerala, India.
Sherin S PaulDepartment of Community Medicine, Malankara Orthodox Syrian Church Medical College, Kolenchery, Kerala, India.
Smitha KrishnamoorthyDepartment of General Medicine, Amrita Institute of Medical Sciences, Kochi, Kerala, India.
Basil T BabyDepartment of Community Medicine, Malankara Orthodox Syrian Church Medical College, Kolenchery, Kerala, India.
Anna MathewDepartment of Pharmacology, Malankara Orthodox Syrian Church Medical College, Kolenchery, Kerala, India.
Balakrishnan R NairSchool of Medicine and Public Health, University of Newcastle, Newcastle, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPotentially inappropriate medications (PIMs) are a major concern in geriatric care. The primary objective of our study was to assess the prevalence of PIMs prescribed for older persons attending outpatient setting of two teaching hospitals in Kerala state in South India, where the population is aging. MATERIALS AND

methodsA cross-sectional study was carried out in two teaching hospitals in Kerala. Four hundred consecutive outpatient medical records of patients aged 65 years and above were selected. The current medications of the patients were analyzed to identify PIMs by the Beers criteria 2015. Polypharmacy and hyperpolypharmacy were defined as 5-9 medications and ≥10 medications, respectively. Chi-square test was done to identify demographic variables and the pattern of health-care facility use associated with PIM prescription. Binary logistic regression was performed to adjust for confounding associations.

resultsThe prevalence of PIMs prescription was 34.0% (95% confidence interval: 29.4%-38.6%) and that of polypharmacy and hyperpolypharmacy was 45.8% and 13.5%, respectively. The common PIMs were proton-pump inhibitors, benzodiazepines, peripheral α-1 blockers, and first-generation antihistamines. Inpatient admission, visits to the emergency department, multiple diagnoses, polypharmacy, and hyperpolypharmacy were associated with PIM prescription (

conclusionPIM prescription appears to be common in teaching hospitals in Kerala. Polypharmacy and hyperpolypharmacy in older people should trigger a review of medication to reduce the use of PIM.

Indexed as

Beers criteriageropharmacologyhyperpolypharmacypolypharmacypotentially inappropriate medications

Identifiers

PMID31572049
PMCPMC6755761

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.