ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2019
Association between metabolic syndrome and limb muscle quantity and quality in older adults: a pilot ultrasound study.
Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Exploring the associations between skeletal muscle echogenicity and physical function in aging adults: A systematic review with meta-analyses.Journal of sport and health science · 2024Pooled it
- Association between handgrip strength and metabolic syndrome: A meta-analysis and systematic review.Frontiers in nutrition · 2022Pooled it
- Article
- Muscle Imaging Assessments in Sarcopenia: A Statement from China National Center for Orthopedics (NCO) and the East Meets West Action Group of the European Calcified Tissue Society (ECTS).Calcified tissue international · 2025Review
- Evaluation of paraspinal muscles in adolescent idiopathic scoliosis: a study based on shear wave elastography.Spine deformity · 2025Article
- Ultrasound evaluation of muscles in older patients with metabolıc syndrome.Irish journal of medical science · 2025Article
- Machine Learning-Based predictive model for adolescent metabolic syndrome: Utilizing data from NHANES 2007-2016.Scientific reports · 2025Article
- Exploring discrepancies in muscle analysis with ImageJ: understanding the impact of tool selection on echo intensity and muscle area measurements.Journal of ultrasound · 2024Article
- Handgrip Strength and Clinical Evolution of People Living with HIV: A Mini Narrative Review.Current HIV research · 2024Review
- Impact of serum carotenoids on cardiovascular mortality risk in middle-aged and elderly adults with metabolic syndrome.Frontiers in nutrition · 2024Article
- Association between Metabolic Syndrome and Musculoskeletal Status: A Cross-Sectional Study of NHANES.International journal of endocrinology · 2024Article
- Suboptimal Tongue Pressure Is Associated with Risk of Malnutrition in Community-Dwelling Older Individuals.Nutrients · 2021Article
- MiRNAs, Myostatin, and Muscle MRI Imaging as Biomarkers of Clinical Features in Becker Muscular Dystrophy.Diagnostics (Basel, Switzerland) · 2020Article
- Ultrasound measurements of superficial and deep masticatory muscles in various postures: reliability and influencers.Scientific reports · 2020Article
- Article
- Ultrasound and radiological features of abdominal unicentric castleman's disease: A case series study.Medicine · 2020Observational
- Three-Dimensional Ankle Exercise with Combined Isotonic Technique for an Obese Subject with Plantar Fasciitis: A Case Study.Medicina (Kaunas, Lithuania) · 2020Article
- High-energy focused extracorporeal shock wave therapy for bone marrow edema syndrome of the hip: A retrospective study.Medicine · 2020Observational
- Masticatory Muscles Activity in Sport Climbers.International journal of environmental research and public health · 2020Article
- Photoacoustic Imaging of Tattoo Inks: Phantom and Clinical Evaluation.Applied sciences (Basel, Switzerland) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeLimited imaging studies have investigated whether limb muscle quantity and quality change after metabolic syndrome (MetS) development. This pilot study examined MetS influence on limb muscle characteristics in older adults.
methodsParticipants were recruited from annual health examinations; their right biceps brachii, triceps brachii, rectus femoris, and gastrocnemius muscles were measured by ultrasound. Anthropometric parameters, blood biochemistry, and physical performance (handgrip strength and gait speed) were also examined.
resultsOverall, 129 participants were enrolled, including 26 with MetS. Although handgrip strength was lower in MetS patients, there were no significant between-group differences considering thickness and mean echogenicity of the four muscles. Handgrip strength was positively correlated with the thickness of biceps brachii, triceps brachii, and rectus femoris but was negatively associated with their echogenicity. On multivariate analysis, triceps muscle echogenicity was trivially associated (odds ratio, 0.93; 95% confidence interval, 0.86-0.99) with MetS, possibly due to multicollinearity with grip strength.
conclusionNo significant difference was recognized in limb muscle thickness and echogenicity in the geriatric population with MetS compared with healthy controls by ultrasound imaging. However, the finding might be caused by the small sample size of our participants. Future large-scale studies should explore the influence of separated risk factors of MetS on limb muscle echotexture and examine whether manifestation differs in different age populations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.