Evidence map›Paper›PMID 31571945›Full record

ArticleInfection and drug resistance2019

A comparison between dexlansoprazole modified release-based and lansoprazole-based nonbismuth quadruple (concomitant) therapy for first-line

Wei-Chen Tai, Chih-Ming Liang, Kuo-Wei Bi, Chung-Mou Kuo, Lung-Sheng Lu, Cheng-Kun Wu, Shih-Cheng Yang, Yuan-Hung Kuo, Chen-Hsiang Lee, Chih-Fang Huang and 6 more

Erratum issued Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT03829150 (Anti-Helicobacter Pylori Therapy With Dexlansoprazole MR-Based Concomitant Quadruple Therapy- A Prospective Randomized Trial), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03829150 nacompletednot on this map

Anti-Helicobacter Pylori Therapy With Dexlansoprazole MR-Based Concomitant Quadruple Therapy- A Prospective Randomized Trial

TypeinterventionalSponsorChang Gung Memorial HospitalRan2017 to 2019Enrolled202ConditionsHelicobacter Pylori InfectionArmsDexlan, Amoxicillin, Clarithromycin 500mg, Metronidazole
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Newer, Older, and Alternative Agents for the Eradication ofAntibiotics (Basel, Switzerland) · 2023
    Review
  4. Article
  5. BestAntibiotics (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Wei-Chen TaiDivision of Hepatogastroenterology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
Chih-Ming LiangDivision of Hepatogastroenterology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.ORCID 0000-0002-6614-5937
Kuo-Wei BiDivision of Chinese Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.ORCID 0000-0001-5486-4080
Chung-Mou KuoDivision of Hepatogastroenterology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
Lung-Sheng LuDivision of Hepatogastroenterology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
Cheng-Kun WuDivision of Hepatogastroenterology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
Shih-Cheng YangDivision of Hepatogastroenterology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
Yuan-Hung KuoDivision of Hepatogastroenterology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
Chen-Hsiang LeeDivision of Infectious Diseases, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
Chih-Fang HuangDivision of Family Physician, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.ORCID 0000-0002-5900-292X
Chien-Ning HsuDepartment of Pharmacy, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.ORCID 0000-0001-7470-528X
Pin-I HsuDivision of Gastroenterology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, National Yang-Ming University, Kaohsiung, Taiwan.
Deng-Chyang WuDivision of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital and Kaohsiung Medical University, Kaohsiung, Taiwan.ORCID 0000-0003-3742-0634
Tsung-Hui HuDivision of Hepatogastroenterology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
Keng-Liang WuDivision of Hepatogastroenterology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.ORCID 0000-0002-8703-6625
Seng-Kee ChuahDivision of Hepatogastroenterology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.ORCID 0000-0002-8934-3223
Kaohsiung Chang Gung Memorial Hospital · TWChang Gung University · TWKaohsiung Medical University · TWNational Yang Ming Chiao Tung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSteadily maintaining high intra-gastric PH is the major factor for successful

methodsTwo hundred two participants with

resultsThe eradication rates in the DACM group were 86.1% [95% confidence interval (CI): 77.8%-92.2%] in the ITT analysis and 90.6% (95% CI: 82.9%-95.6%) in the PP analysis, respectively, as compared with 90.1% (95% CI: 82.6%-95.2%) and 92.6% (95% CI: 85.5%-96.9%) (

conclusionAs a first-line CLINICALTRIALSGOV IDENTIFIER: NCT03829150.

Indexed as

antibiotic resistancedexlansoprazole MR-based concomitant therapyHelicobacter pylori eradicationlansoprazole-based concomitant therapystrong proton-pump inhibitor

Identifiers

PMID31571945
PMCPMC6754331
OpenAlexW2972398987

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.