Evidence map›Paper›PMID 31571922›Full record

ArticleOncoTargets and therapy2019

TNF-like ligand 1A is associated with progression and prognosis of human gastric cancer.

Yaxian Gao, Yuanyuan Wang, Xiao Wang, Yongwei Wang, Xiaoqing Zhang, Xun Sun

Open access · goldAbstract read
In one paragraph

Article in OncoTargets and therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yaxian Gao *Department of Immunology, China Medical University, Shenyang, Liaoning 110000, People's Republic of China.
Yuanyuan Wang *Department of Anesthesiology, The Fourth Affiliated Hospital, China Medical University, Shenyang, Liaoning 110000, People's Republic of China.
Xiao WangDepartment of Immunology, China Medical University, Shenyang, Liaoning 110000, People's Republic of China.ORCID 0000-0002-6217-4941
Yongwei WangDepartment of Anatomy, Chengde Medical College, Chengde, Hebei 067000, People's Republic of China.
Xiaoqing ZhangDepartment of Immunology, China Medical University, Shenyang, Liaoning 110000, People's Republic of China.
Xun SunDepartment of Immunology, China Medical University, Shenyang, Liaoning 110000, People's Republic of China.
China Medical University · CNFourth Affiliated Hospital of China Medical University · CNAffiliated Hospital of Chengde Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to investigate the function of TNF-like ligand 1A (TL1A) in the tumorigenesis and progression of gastric cancer (GC).

methodsRNA-seq gene expression and clinical information for GC patients were obtained from The Cancer Genome Atlas (TCGA) database. Differentially expressed genes (DEGs) between GC tissue samples and normal controls were screened with the edgeR package. Identification of gene co-expression and functional enrichment analyses were performed with Pearson's correlation analysis and gene set enrichment analysis (GSEA), respectively. Lastly, survival analysis was performed using the Kaplan-Meier method with the log rank test.

results

conclusion

Indexed as

co-expression analysisgastric cancerGSEAprognosisTNF-like ligand 1A

Identifiers

PMID31571922
PMCPMC6756834
OpenAlexW2974755678

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.