Evidence map›Paper›PMID 31571891›Full record

ReviewVascular health and risk management2019

When to withhold oral anticoagulation in atrial fibrillation - an overview of frequent clinical discussion topics.

Jaap Seelig, Ron Pisters, Martin E Hemels, Menno V Huisman, Hugo Ten Cate, Marco Alings

Open access · goldAbstract readReview
In one paragraph

Review in Vascular health and risk management, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Intracerebral hemorrhage mortality in individuals with atrial fibrillation: a nationwide analysis of mortality trends in the United States.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Jaap SeeligDepartment of Cardiology, Rijnstate Hospital, Arnhem, The Netherlands.ORCID 0000-0003-0191-0244
Ron PistersDepartment of Cardiology, Rijnstate Hospital, Arnhem, The Netherlands.
Martin E HemelsDepartment of Cardiology, Rijnstate Hospital, Arnhem, The Netherlands.
Menno V HuismanDepartment of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0003-1423-5348
Hugo Ten CateDepartment of Internal Medicine, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands.
Marco AlingsDepartment of Cardiology, Amphia Hospital, Breda, The Netherlands.
Rijnstate Hospital · NLAmphia Ziekenhuis · NLLeiden University Medical Center · NLMaastricht University · NLRadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stroke prevention with oral anticoagulants in patients with atrial fibrillation predisposes for bleeding. As a result, in select patient groups anticoagulation is withheld because of a perceived unfavorable risk-benefit ratio. Reasons for withholding anticoagulation can vary greatly between clinicians, often leading to discussion in daily clinical practice on the best approach. To guide clinical decision-making, we have reviewed available evidence on the most frequently reported reasons for withholding anticoagulation: previous bleeding, frailty and age, and an overall high bleeding risk.

Indexed as

Withholding TreatmentAdministration, OralAge FactorsAnticoagulantsAtrial FibrillationClinical Decision-MakingFrailtyHealth StatusHemorrhageHumansPatient SelectionRisk AssessmentRisk FactorsStrokeAnticoagulantsageanticoagulantsatrial fibrillationfrail elderlyhemorrhage

Identifiers

PMID31571891
PMCPMC6755244
OpenAlexW2973346530

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.