Evidence map›Paper›PMID 31571530›Full record

ArticleThyroid : official journal of the American Thyroid Association2019

A Thyroid Hormone-Independent Molecular Fingerprint of 3,5-Diiodothyronine Suggests a Strong Relationship with Coffee Metabolism in Humans.

Maik Pietzner, Josef Köhrle, Ina Lehmphul, Kathrin Budde, Gabi Kastenmüller, Georg Brabant, Henry Völzke, Anna Artati, Jerzy Adamski, Uwe Völker and 3 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Thyroid : official journal of the American Thyroid Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Cardiovascular Findings and Effects of Caffeine on Experimental Hypothyroidism.Endocrine, metabolic & immune disorders drug targets · 2025
    Article
  2. Article
  3. Observational
  4. Article
  5. Review
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Maik PietznerInstitute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.
Josef KöhrleInstitut für Experimentelle Endokrinologie, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Ina LehmphulInstitut für Experimentelle Endokrinologie, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Kathrin BuddeInstitute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.
Gabi KastenmüllerInstitute of Bioinformatics and Systems Biology, Helmholtz Zentrum München, Neuherberg, Germany.
Georg BrabantMedical Clinic I, University of Lübeck, Lübeck, Germany.
Henry VölzkeDZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany.
Anna ArtatiResearch Unit of Experimental Genetics, Genome Analysis Center, Molecular Endocrinology and Metabolism, Helmholtz Zentrum München, Neuherberg, Germany.
Jerzy AdamskiResearch Unit of Experimental Genetics, Genome Analysis Center, Molecular Endocrinology and Metabolism, Helmholtz Zentrum München, Neuherberg, Germany.
Uwe VölkerDZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany.
Matthias NauckInstitute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.
Nele FriedrichInstitute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.
Georg HomuthDepartment of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
Universitätsmedizin Greifswald · DEHelmholtz Zentrum München · DEHumboldt-Universität zu Berlin · DENational University of Singapore · SGUniversity of Cambridge · GBUniversity of Lübeck · DE

Funding

Medical Research Council MC_UU_12015/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultCaffeineCoffeeDiiodothyroninesDNA FingerprintingFemaleHealthy VolunteersHumansMagnetic Resonance SpectroscopyMaleMass SpectrometryMetabolomicsMiddle AgedReference ValuesThyroid Function TestsThyroid Hormones3,5-diiodothyronineCaffeineCoffeeDiiodothyroninesThyroid HormonesThyrotropinThyroxine3,5-diiodothyroninecaffeine metabolismmetabolomicsthyroidthyrotoxicosis

Identifiers

PMID31571530
PMCPMC6918876
OpenAlexW2978913985

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.