Evidence map›Paper›PMID 31571527›Full record

ArticleEmerging microbes & infections2019

Enterovirus D68-associated respiratory and neurological illness in Spain, 2014-2018.

Rubén González-Sanz, Irene Taravillo, Jordi Reina, Ana Navascués, Antonio Moreno-Docón, Maitane Aranzamendi, María Pilar Romero, Margarita Del Cuerpo, Carmen Pérez-González, Sonia Pérez-Castro and 2 more

Open access · goldAbstract read
In one paragraph

Article in Emerging microbes & infections, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
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  8. Detections of rare enterovirus C105 linked to an emerging novel clade, Spain, 2019 to 2024.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  9. Incidence, clinical manifestations and characterization of Enterovirus in the last decade (2014-2023) in Asturias (Spain). Effect of the SARS-CoV-2 pandemic.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  10. Enhanced echovirus 11 genomic surveillance in neonatal infections in Spain following a European alert reveals new recombinant forms linked to severe cases, 2019 to 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 1 country.

Rubén González-SanzEnterovirus Unit, National Centre for Microbiology, Instituto de Salud Carlos III , Madrid , Spain.
Irene TaravilloEnterovirus Unit, National Centre for Microbiology, Instituto de Salud Carlos III , Madrid , Spain.
Jordi ReinaHospital Son Espases , Palma de Mallorca , Spain.
Ana NavascuésComplejo Hospitalario de Navarra , Navarra , Spain.
Antonio Moreno-DocónHospital Virgen de la Arrixaca , Murcia , Spain.
Maitane AranzamendiHospital Universitario Cruces, Biocruces Bizkaia Health Research Institute , Bilbao , Spain.
María Pilar RomeroHospital La Paz , Madrid , Spain.
Margarita Del CuerpoHospital Santa Creu i Sant Pau , Barcelona , Spain.
Carmen Pérez-GonzálezHospital Dr. Negrín , Las Palmas de Gran Canaria , Spain.
Sonia Pérez-CastroServicio de Microbiología, Complexo Hospitalario Universitario de Vigo (CHUVI) , Sergas, Vigo , Spain.
Almudena OteroEnterovirus Unit, National Centre for Microbiology, Instituto de Salud Carlos III , Madrid , Spain.
María CabrerizoEnterovirus Unit, National Centre for Microbiology, Instituto de Salud Carlos III , Madrid , Spain.ORCID https://orcid.org/0000-0001-7054-5696
Instituto de Salud Carlos III · ESBioCruces Health research Institute · ESComplejo Hospitalario de Navarra · ESHospital de Sant Pau · ESHospital Universitario de Gran Canaria Doctor Negrín · ESHospital Universitario La Paz · ESHospital Universitario Son Espases · ESHospital Universitario Virgen de la Arrixaca · ESUniversity Hospital Complex Of Vigo · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During 2014, enterovirus D68 (EV-D68) outbreaks were described globally, causing severe respiratory diseases in children and, in some cases, subsequent paralysis. In this study, the type characterization of enterovirus (EV) detected in respiratory illnesses and the epidemiology and clinical association of EV-D68 infections in Spain over a five-year period were described. A total of 546 EV-positive samples from hospitalized patients with respiratory infections were included. EV-D68 was the most frequently detected type (46.6%, 191/410 typed EV). Other EV from species A (25.1%), B (27.8%) and C (0.5%) were also identified. EV-D68 infections were more associated with bronchitis while EV-A/B types were more frequent in upper respiratory illness (

Indexed as

AdultAgedAged, 80 and overBronchitisChild, PreschoolEnterovirus D, HumanEnterovirus InfectionsHospitalizationHumansInfantMeningitisMiddle AgedNervous System DiseasesParalysisPhylogenyRespiratory Tract Infectionsacute flaccid paralysisEnterovirusenterovirus D68phylogenetic analysisrespiratory infections

Identifiers

PMID31571527
PMCPMC6781473
OpenAlexW2977608869

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.