Evidence map›Paper›PMID 31571440›Full record

ArticleClinical and experimental emergency medicine2019

Effects of cholesterol levels on outcomes of out-of-hospital cardiac arrest: a cross-sectional study.

Jong Hwan Kim, Dae Han Wi, Jun Hee Lee, Hyung Jun Song, Sang Do Shin, Young Sun Ro, Kwang-Ho Bae

Open access · diamondAbstract read
In one paragraph

Article in Clinical and experimental emergency medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Intra-arrest blood-based biomarkers for out-of-hospital cardiac arrest: A scoping review.Journal of the American College of Emergency Physicians open · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jong Hwan KimDepartment of Emergency Medicine, Wonkwang University Sanbon Hospital, Gunpo, Korea.
Dae Han WiDepartment of Emergency Medicine, Wonkwang University Sanbon Hospital, Wonkwang University School of Medicine, Gunpo, Korea.
Jun Hee LeeDepartment of Emergency Medicine, Wonkwang University Sanbon Hospital, Wonkwang University School of Medicine, Gunpo, Korea.
Hyung Jun SongDepartment of Emergency Medicine, Wonkwang University Sanbon Hospital, Gunpo, Korea.
Sang Do ShinDepartment of Emergency Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Young Sun RoLaboratory of Emergency Medical Services, Seoul National University Hospital Biomedical Research Institute, Seoul, Korea.
Kwang-Ho BaeMibyeong Research Center, Korea Institute of Oriental Medicine, Daejeon, Korea.
Wonkwang University · KRSeoul National University Hospital · KRKorea Institute of Oriental Medicine · KR

Funding

Korea Centers for Disease Control and Prevention 2013E3300500Korea Centers for Disease Control and Prevention 2014E3300100
6 · The paper itself

Abstract

objectiveHigh cholesterol level is a risk factor for coronary artery disease, and coronary artery disease is a major risk factor for out-of-hospital cardiac arrest (OHCA). However, the effect of cholesterol level on outcomes of OHCA has been poorly studied. This study aimed to determine the effect of cholesterol level on outcomes of OHCA.

methodsThis cross-sectional study used the CAPTURES (Cardiac Arrest Pursuit Trial with Unique Registration and Epidemiologic Surveillance) project database in Korea. Multivariable conditional logistic regression analysis was performed to estimate the effect of cholesterol level on outcomes in OHCA.

resultsIn all, 584 cases of OHCA were analyzed; those with cholesterol levels <120 mg/dL were classified as having low total cholesterol (TC) (n=197), those with levels ranging from 120-199 mg/dL as middle TC (n=322), and those with ≥200 mg/dL as high TC (n=65). Compared to low TC, more patients with middle TC and high TC survived to discharge (9.1% vs. 22.0% and 26.2%, respectively, P=0.001). The good cerebral performance category also increased in that order (4.1 % vs. 14.6% and 23.1%, respectively, P≤0.001). Comparing middle TC and high TC with low TC, adjusted odds ratios (95% confidence intervals) were 1.97 (1.06 to 3.64) and 2.53 (1.08 to 5.92) for survival to discharge, respectively, and 2.53 (1.07 to 5.98) and 4.73 (1.63 to 13.71) for good neurological recovery, respectively.

conclusionHigher cholesterol is associated with better outcomes in OHCA; cholesterol level is a good predictor of outcomes of OHCA.

Indexed as

Cardiac Arrest Pursuit Trial with Unique Registration and Epidemiologic SurveillanceCholesterolHeart arrestOutcome

Identifiers

PMID31571440
PMCPMC6774009
OpenAlexW2975828499

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.