ArticleBrain and behavior2019
Monocyte/lymphocyte ratio is associated with carotid stenosis in ischemic stroke: A retrospective analysis.
Article in Brain and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 31 citations in OpenAlex.
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- Symptomatic neurosyphilis in HIV-negative patients: a retrospective cohort study.Frontiers in public health · 2025Article
- The Monocyte-to-Lymphocyte Ratio Was Associated With Intraplaque Neovascularization of the Carotid Artery on AngioPLUS.Brain and behavior · 2024Article
- A low prognostic nutritional index is associated with chronic subdural hematoma recurrence.Neurosurgical review · 2023Article
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- The Correlation Between Aldosterone and Leukocyte-Related Inflammation: A Comparison Between Patients with Primary Aldosteronism and Essential Hypertension.Journal of inflammation research · 2023Article
- Protective Effect of Vitamin D Supplementation on Some Hemogram Derived Inflammatory Indices in Normal and High-Fat Diet Fed Male Wistar Rats.International journal of preventive medicine · 2023Article
- Article
- A PCSK9 inhibitor induces a transient decrease in the neutrophil-lymphocyte ratio and monocyte-lymphocyte ratio in homozygous familial hypercholesterolemia patients.Atherosclerosis plus · 2022Article
- The lymphocyte-to-monocyte ratio predicts intracranial atherosclerotic stenosis plaque instability.Frontiers in immunology · 2022Article
- Monocyte/Lymphocyte Ratio and MCHC as Predictors of Collateral Carotid Artery Disease-Preliminary Report.Journal of personalized medicine · 2021Article
- Monocyte-to-lymphocyte ratio as a predictor of stroke-associated pneumonia: A retrospective study-based investigation.Brain and behavior · 2021Article
- The relationship between ambulatory arterial stiffness, inflammation, blood pressure dipping and cardiovascular outcomes.BMC cardiovascular disorders · 2021Observational
- Monocyte-to-Lymphocyte Ratio is Associated with Depression 3 Months After Stroke.Neuropsychiatric disease and treatment · 2021Article
- The Leukocyte Subtype Counts and Ratios Can Effectively Predict the Risk of Arterial Stiffness Assessed by Cardio-Ankle Vascular Index: A Retrospective Study.Frontiers in cardiovascular medicine · 2021Article
- Evaluation of monocyte-to-high-density lipoprotein cholesterol ratio and monocyte-to-lymphocyte ratio in ischemic stroke.The Journal of international medical research · 2020Article
- Monocyte/lymphocyte ratio is associated with carotid stenosis in ischemic stroke: A retrospective analysis.Brain and behavior · 2019Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCarotid artery stenosis, mainly caused by carotid atherosclerosis, is related to ischemic stroke. This study was to investigate whether monocyte/lymphocyte ratio (MLR) was associated with increased severity of carotid stenosis in patients with ischemic stroke.
methodsA total of 395 participants with ischemic stroke were retrospectively analyzed. The severity of carotid stenosis was evaluated by ultrasound examination. Patients were divided into two groups: nonsevere stenosis group and severe stenosis group. Multivariate logistic analysis was used to evaluate risk factors.
resultsA significant correlation was found between MLR and the severity of carotid stenosis in patients with ischemic stroke. MLR was the independent risk factor of carotid stenosis (OR: 9.74, 95% CI: 1.16-81.54). In the ROC curves analysis, a cutoff value of 0.20 for MLR predicted the severity of carotid stenosis with a sensitivity of 80.40% and specificity of 26.40% (ROC area under the curve: 0.598, 95% CI: 0.53-0.67, p = .004).
conclusionMonocyte/lymphocyte ratio plays important roles in carotid stenosis in patients with ischemic stroke and is an independent risk factor of the severity of carotid stenosis. Therefore, MLR might be considered a potential index in the diagnosis of carotid stenosis in patients with ischemic stroke.
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