ArticleBJOG : an international journal of obstetrics and gynaecology2020
Preterm birth phenotypes in women with autoimmune rheumatic diseases: a population-based cohort study.
Article in BJOG : an international journal of obstetrics and gynaecology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impact of maternal psoriasis on adverse maternal and neonatal outcomes: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2023Pooled it
- Pregnancy Outcomes in Women With Systemic Sclerosis Before and/or After Diagnosis and by Parity: A Swedish Population-Based Cohort Study.Arthritis & rheumatology (Hoboken, N.J.) · 2026Article
- Perinatal vulnerability: its impact on oral and craniofacial hard tissue development.Frontiers in physiology · 2026Review
- Maternal and neonatal outcomes in pregnancies with rheumatoid arthritis, psoriatic arthritis, and spondyloarthritis: a comparative study.BMC rheumatology · 2025Article
- Risk of preterm delivery and early pregnancy hydroxychloroquine use from a Californian lupus cohort.Lupus science & medicine · 2025Article
- Th17/Treg Cell Imbalance May Contribute to Spontaneous Preterm Labor.Journal of immunology research · 2025Review
- Effects of famotidine use during pregnancy: an observational cohort study.Journal of pharmaceutical health care and sciences · 2024Article
- Considering pregnancies as repeated vs independent events: an empirical comparison of common approaches across selected perinatal outcomes.American journal of obstetrics & gynecology MFM · 2024Article
- Detection of potential safety signals related to the use of remdesivir and tocilizumab in the COVID era during pregnancy, resorting to open data from the FDA adverse event reporting system (FAERS).Frontiers in pharmacology · 2024Article
- Pregnancy and Inflammatory Rheumatological Diseases: A Single-Center Retrospective Cohort Study.Cureus · 2023Article
- Trends and Determinants of Operative Vaginal Delivery at Two Academic Hospitals in Johannesburg, South Africa 2005-2019.International journal of environmental research and public health · 2022Article
- Maternal leucocyte trajectory across pregnancy associated with offspring's growth.Pediatric research · 2022Article
- Adverse Perinatal Outcomes Before and After Diagnosis of Systemic Lupus Erythematosus Among African American Women.Arthritis care & research · 2022Article
- Pregnancy in juvenile idiopathic arthritis: maternal and foetal outcome, and impact on disease activity.Therapeutic advances in musculoskeletal disease · 2022Article
- Article
- A hierarchical procedure to select intrauterine and extrauterine factors for methodological validation of preterm birth risk estimation.BMC pregnancy and childbirth · 2021Article
- Chronic histiocytic intervillositis: A breakdown in immune tolerance comparable to allograft rejection?American journal of reproductive immunology (New York, N.Y. : 1989) · 2021Review
- Article
- Retrospective cohort study of pregnancy outcomes in hidradenitis suppurativa.The British journal of dermatology · 2020Article
- Pregnancy outcomes in women with idiopathic inflammatory myopathy, before and after diagnosis-a population-based study.Rheumatology (Oxford, England) · 2020Article
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9 authors.
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Abstract
objectiveTo investigate preterm birth (PTB) phenotypes in women with different autoimmune rheumatic diseases in a large population-based cohort.
designRetrospective cohort study.
settingCalifornia, USA. POPULATION: All live singleton births in California between 2007 and 2011 were analysed. Patients with autoimmune disease at delivery were identified by International Classification of Diseases, Ninth Revision , Clinical Modification (ICD-9-CM), codes for systemic lupus erythematosus (SLE), systemic sclerosis (SSc), rheumatoid arthritis (RA), polymyositis/dermatomyositis (DM/PM), and juvenile idiopathic arthritis (JIA).
methodsMaternally linked hospital and birth certificate records of 2 481 516 deliveries were assessed (SLE n = 2272, RA n = 1501, SSc n = 88, JIA n = 187, DM/PM n = 38). Multivariable Poisson regression models estimated the risk ratios (RRs) for different PTB phenotypes (relative to term deliveries) for each autoimmune disease compared with the general obstetric population, adjusting for maternal age, race/ethnicity, body mass index, smoking, education, payer, parity, and prenatal care.
main outcome measuresPreterm birth (PTB) was assessed overall (20-36 weeks of gestation) and by subphenotype: preterm prelabour rupture of membranes (PPROM), spontaneous birth, or medically indicated PTB. The risk of PTB overall and for each phenotype was partitioned by gestational age: early (20-31 weeks of gestation) and late (32-36 weeks of gestation).
resultsRisks for PTB were elevated for each autoimmune disease evaluated: SLE (RR 3.27, 95% CI 3.01-3.56), RA (RR 2.04, 95% CI 1.79-2.33), SSc (RR 3.74, 95% CI 2.51-5.58), JIA (RR 2.23, 95% CI 1.54-3.23), and DM/PM (RR 5.26, 95% CI 3.12-8.89). These elevated risks were observed for the majority of PTB phenotypes as well.
conclusionsWomen with systemic autoimmune diseases appear to have an elevated risk of various PTB phenotypes. Therefore, preconception counselling and close monitoring during pregnancy is crucial. TWEETABLE ABSTRACT: This study found that women with systemic autoimmune diseases have an elevated risk of preterm birth phenotypes.
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