ReviewHippocampus2020
Is hippocampal remapping the physiological basis for context?
Review in Hippocampus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed.
- Hippocampal communication with the anterior olfactory nucleus is necessary for context-dependent odor memory.Behavioral neuroscience · 2026Article
- Disorganized Inhibitory Dynamics in Hippocampal area CA1 of 22q11.2 Deletion Mutant Mice.bioRxiv : the preprint server for biology · 2026Article
- Article
- Emotional shaping of spatial encoding along the dorsal ventral axis of the hippocampus.Frontiers in systems neuroscience · 2026Review
- The relevance of context in memory tasks influences the magnitude of hippocampal remapping.Cell reports · 2025Article
- Adaptation of hippocampal spatial and contextual representations to task structure.Science advances · 2025Article
- Anxiety and Beyond: Diversity in Ventral Hippocampus Circuits and Function.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- REMI: Reconstructing Episodic Memory During Internally Driven Path Planning.bioRxiv : the preprint server for biology · 2025Article
- Time Makes Space: Emergence of Place Fields in Networks Encoding Temporally Continuous Sensory Experiences.bioRxiv : the preprint server for biology · 2025Article
- Exploring replay.Nature communications · 2025Article
- Trading Place for Space: Increasing Location Resolution Reduces Contextual Capacity in Hippocampal Codes.bioRxiv : the preprint server for biology · 2025Article
- Hidden state inference requires abstract contextual representations in the ventral hippocampus.Science (New York, N.Y.) · 2024Article
- Space is a latent sequence: A theory of the hippocampus.Science advances · 2024Article
- Extended Poisson Gaussian-Process Latent Variable Model for Unsupervised Neural Decoding.Neural computation · 2024Article
- Mice integrate conspecific and contextual information in forming social episodic-like memories under spontaneous recognition task conditions.Scientific reports · 2024Article
- Remapping revisited: how the hippocampus represents different spaces.Nature reviews. Neuroscience · 2024Review
- Working memory features are embedded in hippocampal place fields.Cell reports · 2024Article
- Adult Neurogenesis, Context Encoding, and Pattern Separation: A Pathway for Treating Overgeneralization.Advances in neurobiology · 2024Review
- Global remapping emerges as the mechanism for renewal of context-dependent behavior in a reinforcement learning model.Frontiers in computational neuroscience · 2024Article
- Adult-born granule cells facilitate remapping of spatial and non-spatial representations in the dentate gyrus.Neuron · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
In 1980, Nadel and Wilner extended Richard Hirsh's notion that the hippocampus creates environmental representations, called "contexts," suggesting that the fundamental structure of context was the spatial representation proposed by O'Keefe and Nadel's landmark book, The Hippocampus as a Cognitive Map (1978). This book, in turn, derives from the discovery that individual hippocampal neurons act as place cells, with the complete set of place cells tiling an enclosure, forming a type of spatial map. It was found that unique environments had unique place cell representations. That is, if one takes the hippocampal map of a specific environment, this representation scrambles, or "remaps" when the animal is placed in a different environment. Several authors have speculated that "maps" and "remapping" form the physiological substrates for context and context shifting. One difficulty with this definition is that it is exclusively spatial; it can only be inferred when an animal locomotes in an enclosure. There are five aims for this article. The first is to give an historical overview of context as a variable that controls behavior. The second aim is to give an historical overview of concepts of place cell maps and remapping. The third aim is to propose an updated definition of a place cell map, based on temporal rather than spatial overlaps, which adds flexibility. The fourth aim is to address the issue of whether the biological phenomenon of hippocampal remapping, is, in fact, the substrate for shifts in the psychological phenomenon of context. The final aim is speculation of how contextual representations may contribute to effective behavior.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.